Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)

Background: Dyslipidemia (DL) is an important risk factor of coronary artery disease (CAD). We evaluated DL prevalence and its 5-year incidence rate in southeastern Iran, to assess the severity and growth rate of this CAD risk factor in the region. Materials and Methods: This study was a part of the...

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Autores principales:	Hamid Najafipour, Gholamreza Yousefzadeh, Mohammad Reza Baneshi, Milad Ahmadi Gohari, Beydolah Shahouzehi, Mitra Shadkam Farokhi, Ali Mirzazadeh
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	coronary artery disease dyslipidemia incidence rate prevalence Medicine R
Acceso en línea:	https://doaj.org/article/bae5aaa271ad4d5087ce808c183bcf93
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spelling	oai:doaj.org-article:bae5aaa271ad4d5087ce808c183bcf932021-11-12T10:25:23ZPrevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)1735-19951735-713610.4103/jrms.JRMS_748_20https://doaj.org/article/bae5aaa271ad4d5087ce808c183bcf932021-01-01T00:00:00Zhttp://www.jmsjournal.net/article.asp?issn=1735-1995;year=2021;volume=26;issue=1;spage=99;epage=99;aulast=Najafipourhttps://doaj.org/toc/1735-1995https://doaj.org/toc/1735-7136Background: Dyslipidemia (DL) is an important risk factor of coronary artery disease (CAD). We evaluated DL prevalence and its 5-year incidence rate in southeastern Iran, to assess the severity and growth rate of this CAD risk factor in the region. Materials and Methods: This study was a part of the Kerman CAD Risk Factors Study Phase 2 (2014–2018) among 9996 individuals aged 15–80 years, from whom 2820 individuals had also participated in Phase 1 (2009–2011). In mg/dl, cholesterol ≥240 and/or low-density lipoprotein cholesterol ≥160 and/or high-density lipoprotein cholesterol <40 for men and <50 for women and/or triglyceride >200 were defined as DL. Results: The lipid profile of 9911 persons was analyzed. Overall 19.6% had borderline cholesterol and 6.4% suffered from hypercholesterolemia. 56.6% of the population (62.5% of females vs. 48.5% of males) suffer from DL, from whom 73.4% were undiagnosed. Female gender, advanced age, obesity, hypertension, diabetes, anxiety, and depression predicted DL in the study population. The prevalence of DL was significantly lower in Phase 2 (56.6%) compared to Phase 1 (81.4%). The prevalence of undiagnosed DL (UDL) and diagnosed DL (DDL) was 40.7% and 16.2%, respectively. The 5-year incidence rate of DL was 2.58 persons/100 person-years (3.24 in females vs. 2.20 in males). Conclusion: Although there were promising signs of a reduction in DL and increase in DDL in the last 5 years, a high percentage of the population have DL yet, from whom mostly are undiagnosed. DL was significantly associated with other CAD risk factors. Therefore, the health-care management system should improve its strategies to reduce the health burden of DL.Hamid NajafipourGholamreza YousefzadehMohammad Reza BaneshiMilad Ahmadi GohariBeydolah ShahouzehiMitra Shadkam FarokhiAli MirzazadehWolters Kluwer Medknow Publicationsarticlecoronary artery diseasedyslipidemiaincidence rateprevalenceMedicineRENJournal of Research in Medical Sciences, Vol 26, Iss 1, Pp 99-99 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	coronary artery disease dyslipidemia incidence rate prevalence Medicine R
spellingShingle	coronary artery disease dyslipidemia incidence rate prevalence Medicine R Hamid Najafipour Gholamreza Yousefzadeh Mohammad Reza Baneshi Milad Ahmadi Gohari Beydolah Shahouzehi Mitra Shadkam Farokhi Ali Mirzazadeh Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
description	Background: Dyslipidemia (DL) is an important risk factor of coronary artery disease (CAD). We evaluated DL prevalence and its 5-year incidence rate in southeastern Iran, to assess the severity and growth rate of this CAD risk factor in the region. Materials and Methods: This study was a part of the Kerman CAD Risk Factors Study Phase 2 (2014–2018) among 9996 individuals aged 15–80 years, from whom 2820 individuals had also participated in Phase 1 (2009–2011). In mg/dl, cholesterol ≥240 and/or low-density lipoprotein cholesterol ≥160 and/or high-density lipoprotein cholesterol <40 for men and <50 for women and/or triglyceride >200 were defined as DL. Results: The lipid profile of 9911 persons was analyzed. Overall 19.6% had borderline cholesterol and 6.4% suffered from hypercholesterolemia. 56.6% of the population (62.5% of females vs. 48.5% of males) suffer from DL, from whom 73.4% were undiagnosed. Female gender, advanced age, obesity, hypertension, diabetes, anxiety, and depression predicted DL in the study population. The prevalence of DL was significantly lower in Phase 2 (56.6%) compared to Phase 1 (81.4%). The prevalence of undiagnosed DL (UDL) and diagnosed DL (DDL) was 40.7% and 16.2%, respectively. The 5-year incidence rate of DL was 2.58 persons/100 person-years (3.24 in females vs. 2.20 in males). Conclusion: Although there were promising signs of a reduction in DL and increase in DDL in the last 5 years, a high percentage of the population have DL yet, from whom mostly are undiagnosed. DL was significantly associated with other CAD risk factors. Therefore, the health-care management system should improve its strategies to reduce the health burden of DL.
format	article
author	Hamid Najafipour Gholamreza Yousefzadeh Mohammad Reza Baneshi Milad Ahmadi Gohari Beydolah Shahouzehi Mitra Shadkam Farokhi Ali Mirzazadeh
author_facet	Hamid Najafipour Gholamreza Yousefzadeh Mohammad Reza Baneshi Milad Ahmadi Gohari Beydolah Shahouzehi Mitra Shadkam Farokhi Ali Mirzazadeh
author_sort	Hamid Najafipour
title	Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
title_short	Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
title_full	Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
title_fullStr	Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
title_full_unstemmed	Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)
title_sort	prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in iran: results of the kerman coronary artery disease risk factors study (phase 2)
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/bae5aaa271ad4d5087ce808c183bcf93
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Prevalence and 5-year incidence rate of dyslipidemia and its association with other coronary artery disease risk factors in Iran: Results of the Kerman coronary artery disease risk factors study (Phase 2)

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