Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling
The Snf1-related kinase (SNRK) is widely expressed and yet its function is poorly understood. Here the authors show that SNRK regulates mitochondrial coupling via the Trib3-PPARα-UCP3 pathway and that cardiac overexpression of SNRK decreases metabolic substrate usage and oxygen consumption but maint...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/bae6e26f24c34045be0fbe2c38eff574 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|