Alpha-2-glycoprotein 1(AZGP1) regulates biological behaviors of LoVo cells by down-regulating mTOR signaling pathway and endogenous fatty acid synthesis.
AZGP1 is a multifaceted protein associated with lipid mobilization, a process that is regulated by FASN and other metabolic pathways such as mTOR signaling. The active mTOR signaling pathway has been found to be involved in a variety of tumors. However, it remains unclear whether it is involved in t...
Saved in:
Main Authors: | Ligong Chang, Xiaoqiang Tian, Yinghui Lu, Min Jia, Peng Wu, Peilin Huang |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/bae70612ecdf42d28c012f55d52238d6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
mTOR-mediated phosphorylation of VAMP8 and SCFD1 regulates autophagosome maturation
by: Hong Huang, et al.
Published: (2021) -
pH-sensitive nanomicelles for controlled and efficient drug delivery to human colorectal carcinoma LoVo cells.
by: Shi-Ting Feng, et al.
Published: (2014) -
Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
by: Farid Ahmad Siddiqui, et al.
Published: (2018) -
Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients
by: Ya-Kun Zhang, et al.
Published: (2017) -
Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells
by: Xinhui Zhou, et al.
Published: (2017)