Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice.

Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice.

<h4>Aim</h4>To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS).<h4>Methods</h4>Peripheral neuropathic pain (PNP) induced by partial sciatic nerve ligation (pSNL) model was assessed in mi...

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Main Authors: Xin Luo, Wai Lydia Tai, Liting Sun, Qiu Qiu, Zhengyuan Xia, Sookja Kim Chung, Chi Wai Cheung
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/baece4fdcba340a095d59d3f96ca0ab4
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