Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis

Video capsule endoscopy (VCE) is an effective diagnostic modality for detecting small bowel lesions. However, the value of VCE for patients with chronic recurrent abdominal pain (CAP) of unknown etiology remains obscure. We retrospectively analyzed factors that could predict enteropathy based on the...

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Autores principales:	Wonshik Kim, Beomjae Lee, Ahyoung Yoo, Seunghan Kim, Moonkyung Joo, Jong-Jae Park
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	chronic abdominal pain video capsule endoscopy inflammatory markers Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/baed51f9a00b472baa100db7d2fc3a0f
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spelling	oai:doaj.org-article:baed51f9a00b472baa100db7d2fc3a0f2021-11-25T17:21:48ZPredictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis10.3390/diagnostics111121232075-4418https://doaj.org/article/baed51f9a00b472baa100db7d2fc3a0f2021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/2123https://doaj.org/toc/2075-4418Video capsule endoscopy (VCE) is an effective diagnostic modality for detecting small bowel lesions. However, the value of VCE for patients with chronic recurrent abdominal pain (CAP) of unknown etiology remains obscure. We retrospectively analyzed factors that could predict enteropathy based on the medical records of 65 patients with unexplained chronic recurrent abdominal pain (CAP) who were assessed using VCE between 2001 and 2021. We also conducted a systematic review and meta-analysis of the literature to validate our results. The positive findings of 27 (41.5%) of the 65 patients were mostly ulcerative lesions including stricture (<i>n</i> = 14, 60.9%) and erosion (<i>n</i> = 8, 29.7%). Multivariate analysis identified elevated ESR (OR, 1.06, 95% CI, 1.02–1.1, <i>p</i> = 0.004) as a significant risk factor for enteropathy predicted by VCE. Three eligible studies in the meta-analysis included 523 patients with CAP. Elevated C-reactive protein (CRP) (OR, 14.09; 95% CI, 2.81–70.60; <i>p</i> = 0.001) and erythrocyte sedimentation rate (ESR) (OR, 14.45; 95% CI, 0.92–227.33; <i>p</i> = 0.06) indicated VCE-positive findings in patients with unexplained abdominal pain. Elevated levels of the inflammatory markers ESR and CRP can thus predict positive VCE findings in patients with CAP.Wonshik KimBeomjae LeeAhyoung YooSeunghan KimMoonkyung JooJong-Jae ParkMDPI AGarticlechronic abdominal painvideo capsule endoscopyinflammatory markersMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 2123, p 2123 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic abdominal pain video capsule endoscopy inflammatory markers Medicine (General) R5-920
spellingShingle	chronic abdominal pain video capsule endoscopy inflammatory markers Medicine (General) R5-920 Wonshik Kim Beomjae Lee Ahyoung Yoo Seunghan Kim Moonkyung Joo Jong-Jae Park Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
description	Video capsule endoscopy (VCE) is an effective diagnostic modality for detecting small bowel lesions. However, the value of VCE for patients with chronic recurrent abdominal pain (CAP) of unknown etiology remains obscure. We retrospectively analyzed factors that could predict enteropathy based on the medical records of 65 patients with unexplained chronic recurrent abdominal pain (CAP) who were assessed using VCE between 2001 and 2021. We also conducted a systematic review and meta-analysis of the literature to validate our results. The positive findings of 27 (41.5%) of the 65 patients were mostly ulcerative lesions including stricture (<i>n</i> = 14, 60.9%) and erosion (<i>n</i> = 8, 29.7%). Multivariate analysis identified elevated ESR (OR, 1.06, 95% CI, 1.02–1.1, <i>p</i> = 0.004) as a significant risk factor for enteropathy predicted by VCE. Three eligible studies in the meta-analysis included 523 patients with CAP. Elevated C-reactive protein (CRP) (OR, 14.09; 95% CI, 2.81–70.60; <i>p</i> = 0.001) and erythrocyte sedimentation rate (ESR) (OR, 14.45; 95% CI, 0.92–227.33; <i>p</i> = 0.06) indicated VCE-positive findings in patients with unexplained abdominal pain. Elevated levels of the inflammatory markers ESR and CRP can thus predict positive VCE findings in patients with CAP.
format	article
author	Wonshik Kim Beomjae Lee Ahyoung Yoo Seunghan Kim Moonkyung Joo Jong-Jae Park
author_facet	Wonshik Kim Beomjae Lee Ahyoung Yoo Seunghan Kim Moonkyung Joo Jong-Jae Park
author_sort	Wonshik Kim
title	Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
title_short	Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
title_full	Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
title_fullStr	Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
title_full_unstemmed	Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis
title_sort	predictors of positive video capsule endoscopy findings for chronic unexplained abdominal pain: single-center retrospective study and meta-analysis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/baed51f9a00b472baa100db7d2fc3a0f
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Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis

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