Evolution of multiple cell clones over a 29-year period of a CLL patient
Studying the genetic progression of many cancers is difficult as longitudinal samples are rarely available. Here, the authors analyse a patient with chronic lymphocytic leukaemia over a 29 year period and track the clonal evolution of the patient’s disease and response to therapy.
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Nature Portfolio
2016
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oai:doaj.org-article:baef2f4116554396b7b5cc41c7e33bf12021-12-02T16:49:26ZEvolution of multiple cell clones over a 29-year period of a CLL patient10.1038/ncomms137652041-1723https://doaj.org/article/baef2f4116554396b7b5cc41c7e33bf12016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13765https://doaj.org/toc/2041-1723Studying the genetic progression of many cancers is difficult as longitudinal samples are rarely available. Here, the authors analyse a patient with chronic lymphocytic leukaemia over a 29 year period and track the clonal evolution of the patient’s disease and response to therapy.Zhikun ZhaoLynn GoldinShiping LiuLiang WuWeiyin ZhouHong LouQichao YuShirley X. TsangMiaomiao JiangFuqiang LiMaryLou McMasterYang LiXinxin LinZhifeng WangLiqin XuGerald MartiGuibo LiKui WuMeredith YeagerHuanming YangXun XuStephen J. ChanockBo LiYong HouNeil CaporasoMichael DeanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Zhikun Zhao Lynn Goldin Shiping Liu Liang Wu Weiyin Zhou Hong Lou Qichao Yu Shirley X. Tsang Miaomiao Jiang Fuqiang Li MaryLou McMaster Yang Li Xinxin Lin Zhifeng Wang Liqin Xu Gerald Marti Guibo Li Kui Wu Meredith Yeager Huanming Yang Xun Xu Stephen J. Chanock Bo Li Yong Hou Neil Caporaso Michael Dean Evolution of multiple cell clones over a 29-year period of a CLL patient |
| description |
Studying the genetic progression of many cancers is difficult as longitudinal samples are rarely available. Here, the authors analyse a patient with chronic lymphocytic leukaemia over a 29 year period and track the clonal evolution of the patient’s disease and response to therapy. |
| format |
article |
| author |
Zhikun Zhao Lynn Goldin Shiping Liu Liang Wu Weiyin Zhou Hong Lou Qichao Yu Shirley X. Tsang Miaomiao Jiang Fuqiang Li MaryLou McMaster Yang Li Xinxin Lin Zhifeng Wang Liqin Xu Gerald Marti Guibo Li Kui Wu Meredith Yeager Huanming Yang Xun Xu Stephen J. Chanock Bo Li Yong Hou Neil Caporaso Michael Dean |
| author_facet |
Zhikun Zhao Lynn Goldin Shiping Liu Liang Wu Weiyin Zhou Hong Lou Qichao Yu Shirley X. Tsang Miaomiao Jiang Fuqiang Li MaryLou McMaster Yang Li Xinxin Lin Zhifeng Wang Liqin Xu Gerald Marti Guibo Li Kui Wu Meredith Yeager Huanming Yang Xun Xu Stephen J. Chanock Bo Li Yong Hou Neil Caporaso Michael Dean |
| author_sort |
Zhikun Zhao |
| title |
Evolution of multiple cell clones over a 29-year period of a CLL patient |
| title_short |
Evolution of multiple cell clones over a 29-year period of a CLL patient |
| title_full |
Evolution of multiple cell clones over a 29-year period of a CLL patient |
| title_fullStr |
Evolution of multiple cell clones over a 29-year period of a CLL patient |
| title_full_unstemmed |
Evolution of multiple cell clones over a 29-year period of a CLL patient |
| title_sort |
evolution of multiple cell clones over a 29-year period of a cll patient |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/baef2f4116554396b7b5cc41c7e33bf1 |
| work_keys_str_mv |
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| _version_ |
1718383358241669120 |