Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions

Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, t...

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Autores principales: Tessa J. Nash, Katrina M. Morris, Neil A. Mabbott, Lonneke Vervelde
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9
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spelling oai:doaj.org-article:baf12b80ee7b4780a418e0eb7d08e8a92021-12-02T16:30:46ZInside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions10.1038/s42003-021-01901-z2399-3642https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a92021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01901-zhttps://doaj.org/toc/2399-3642Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research.Tessa J. NashKatrina M. MorrisNeil A. MabbottLonneke VerveldeNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Tessa J. Nash
Katrina M. Morris
Neil A. Mabbott
Lonneke Vervelde
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
description Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research.
format article
author Tessa J. Nash
Katrina M. Morris
Neil A. Mabbott
Lonneke Vervelde
author_facet Tessa J. Nash
Katrina M. Morris
Neil A. Mabbott
Lonneke Vervelde
author_sort Tessa J. Nash
title Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_short Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_full Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_fullStr Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_full_unstemmed Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_sort inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9
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AT katrinammorris insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions
AT neilamabbott insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions
AT lonnekevervelde insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions
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