Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, t...
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Nature Portfolio
2021
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oai:doaj.org-article:baf12b80ee7b4780a418e0eb7d08e8a92021-12-02T16:30:46ZInside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions10.1038/s42003-021-01901-z2399-3642https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a92021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01901-zhttps://doaj.org/toc/2399-3642Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research.Tessa J. NashKatrina M. MorrisNeil A. MabbottLonneke VerveldeNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
description |
Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research. |
format |
article |
author |
Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde |
author_facet |
Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde |
author_sort |
Tessa J. Nash |
title |
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
title_short |
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
title_full |
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
title_fullStr |
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
title_full_unstemmed |
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
title_sort |
inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9 |
work_keys_str_mv |
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1718383896115019776 |