Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions

Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, t...

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Main Authors:	Tessa J. Nash, Katrina M. Morris, Neil A. Mabbott, Lonneke Vervelde
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9
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spelling	oai:doaj.org-article:baf12b80ee7b4780a418e0eb7d08e8a92021-12-02T16:30:46ZInside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions10.1038/s42003-021-01901-z2399-3642https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a92021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01901-zhttps://doaj.org/toc/2399-3642Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research.Tessa J. NashKatrina M. MorrisNeil A. MabbottLonneke VerveldeNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
description	Nash et al. develop and characterise multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts, which constitute an accessible model of the chicken intestine. This model enables manipulations, such as viral infection, to be performed without the need for micro-injection, thus opening up more opportunities to explore epithelial and leukocyte interactions and responses in host–pathogen, food science and pharmaceutical research.
format	article
author	Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde
author_facet	Tessa J. Nash Katrina M. Morris Neil A. Mabbott Lonneke Vervelde
author_sort	Tessa J. Nash
title	Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_short	Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_full	Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_fullStr	Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_full_unstemmed	Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
title_sort	inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/baf12b80ee7b4780a418e0eb7d08e8a9
work_keys_str_mv	AT tessajnash insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions AT katrinammorris insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions AT neilamabbott insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions AT lonnekevervelde insideoutchickenenteroidswithleukocytecomponentasamodeltostudyhostpathogeninteractions
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Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions

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