Anomalous X-ray diffraction studies of ion transport in K+ channels
The number of K+ occupied binding sites in the selectivity filter of potassium ion channels is still under debate. Here, the authors collect diffraction data on the K+ selective NaK channel NaK2K at a wavelength of 3.35 Å, close to the K absorption edge, revealing that all four binding sites in the...
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Nature Portfolio
2018
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oai:doaj.org-article:bafe95be81dc4ff48f38b4eebc5763462021-12-02T15:33:40ZAnomalous X-ray diffraction studies of ion transport in K+ channels10.1038/s41467-018-06957-w2041-1723https://doaj.org/article/bafe95be81dc4ff48f38b4eebc5763462018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06957-whttps://doaj.org/toc/2041-1723The number of K+ occupied binding sites in the selectivity filter of potassium ion channels is still under debate. Here, the authors collect diffraction data on the K+ selective NaK channel NaK2K at a wavelength of 3.35 Å, close to the K absorption edge, revealing that all four binding sites in the selectivity filter are fully occupied by K+ ions.Patricia S. LanganVenu Gopal VandavasiKevin L. WeissPavel V. AfonineKamel el OmariRamona DumanArmin WagnerLeighton CoatesNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-5 (2018) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Patricia S. Langan Venu Gopal Vandavasi Kevin L. Weiss Pavel V. Afonine Kamel el Omari Ramona Duman Armin Wagner Leighton Coates Anomalous X-ray diffraction studies of ion transport in K+ channels |
| description |
The number of K+ occupied binding sites in the selectivity filter of potassium ion channels is still under debate. Here, the authors collect diffraction data on the K+ selective NaK channel NaK2K at a wavelength of 3.35 Å, close to the K absorption edge, revealing that all four binding sites in the selectivity filter are fully occupied by K+ ions. |
| format |
article |
| author |
Patricia S. Langan Venu Gopal Vandavasi Kevin L. Weiss Pavel V. Afonine Kamel el Omari Ramona Duman Armin Wagner Leighton Coates |
| author_facet |
Patricia S. Langan Venu Gopal Vandavasi Kevin L. Weiss Pavel V. Afonine Kamel el Omari Ramona Duman Armin Wagner Leighton Coates |
| author_sort |
Patricia S. Langan |
| title |
Anomalous X-ray diffraction studies of ion transport in K+ channels |
| title_short |
Anomalous X-ray diffraction studies of ion transport in K+ channels |
| title_full |
Anomalous X-ray diffraction studies of ion transport in K+ channels |
| title_fullStr |
Anomalous X-ray diffraction studies of ion transport in K+ channels |
| title_full_unstemmed |
Anomalous X-ray diffraction studies of ion transport in K+ channels |
| title_sort |
anomalous x-ray diffraction studies of ion transport in k+ channels |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/bafe95be81dc4ff48f38b4eebc576346 |
| work_keys_str_mv |
AT patriciaslangan anomalousxraydiffractionstudiesofiontransportinkchannels AT venugopalvandavasi anomalousxraydiffractionstudiesofiontransportinkchannels AT kevinlweiss anomalousxraydiffractionstudiesofiontransportinkchannels AT pavelvafonine anomalousxraydiffractionstudiesofiontransportinkchannels AT kamelelomari anomalousxraydiffractionstudiesofiontransportinkchannels AT ramonaduman anomalousxraydiffractionstudiesofiontransportinkchannels AT arminwagner anomalousxraydiffractionstudiesofiontransportinkchannels AT leightoncoates anomalousxraydiffractionstudiesofiontransportinkchannels |
| _version_ |
1718387046669615104 |