Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis

Background. Spread of childhood obesity is associated with social and economic factors of modern lifestyle that alter food preferences and lead to sedentary life. Nowadays fatty hepatosis is considered a hepatic manifestation of the metabolic syndrome, which is linked to the rising prevalence of obe...

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Autores principales:	Oksana A. Gavrilova, Lyubov V. Rychkova, Marina A. Darenskaya, Lyudmila A. Grebenkina, Olga V. Kravtsova, Larisa V. Natyaganova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	lipid peroxidation antioxidant protection adolescents obesity fatty hepatosis Science Q
Acceso en línea:	https://doaj.org/article/bb0031e900064ee6bff155929e129b14
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spelling	oai:doaj.org-article:bb0031e900064ee6bff155929e129b142021-11-23T06:14:41ZChange of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis2541-94202587-959610.29413/ABS.2019-4.1.1https://doaj.org/article/bb0031e900064ee6bff155929e129b142019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1971https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. Spread of childhood obesity is associated with social and economic factors of modern lifestyle that alter food preferences and lead to sedentary life. Nowadays fatty hepatosis is considered a hepatic manifestation of the metabolic syndrome, which is linked to the rising prevalence of obesity among the population. There is evidence of a correlation between metabolic disorders and oxidative stress reactions.Aims. To study characteristics of lipid peroxidation system and antioxidant defense processes in adolescents with fatty hepatosis.Materials and methods. We examined 15 adolescents with obesity and fatty hepatosis, 20 adolescents with obesity and without fatty hepatosis, and 20 apparently healthy adolescents, who formed the control group. Spectrophotometric and fluorometric methods were used in the research.Results. We found that some components of antioxidant status of adolescents with obesity and fatty hepatosis were decreased, both in comparison with the group with obesity without hepatosis and control group.Conclusions. It is recommended that patients with obesity and fatty hepatosis take antioxidants in addition to metabolic therapy.Oksana A. GavrilovaLyubov V. RychkovaMarina A. DarenskayaLyudmila A. GrebenkinaOlga V. KravtsovaLarisa V. NatyaganovaScientific Сentre for Family Health and Human Reproduction Problemsarticlelipid peroxidationantioxidant protectionadolescentsobesityfatty hepatosisScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 9-13 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	lipid peroxidation antioxidant protection adolescents obesity fatty hepatosis Science Q
spellingShingle	lipid peroxidation antioxidant protection adolescents obesity fatty hepatosis Science Q Oksana A. Gavrilova Lyubov V. Rychkova Marina A. Darenskaya Lyudmila A. Grebenkina Olga V. Kravtsova Larisa V. Natyaganova Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
description	Background. Spread of childhood obesity is associated with social and economic factors of modern lifestyle that alter food preferences and lead to sedentary life. Nowadays fatty hepatosis is considered a hepatic manifestation of the metabolic syndrome, which is linked to the rising prevalence of obesity among the population. There is evidence of a correlation between metabolic disorders and oxidative stress reactions.Aims. To study characteristics of lipid peroxidation system and antioxidant defense processes in adolescents with fatty hepatosis.Materials and methods. We examined 15 adolescents with obesity and fatty hepatosis, 20 adolescents with obesity and without fatty hepatosis, and 20 apparently healthy adolescents, who formed the control group. Spectrophotometric and fluorometric methods were used in the research.Results. We found that some components of antioxidant status of adolescents with obesity and fatty hepatosis were decreased, both in comparison with the group with obesity without hepatosis and control group.Conclusions. It is recommended that patients with obesity and fatty hepatosis take antioxidants in addition to metabolic therapy.
format	article
author	Oksana A. Gavrilova Lyubov V. Rychkova Marina A. Darenskaya Lyudmila A. Grebenkina Olga V. Kravtsova Larisa V. Natyaganova
author_facet	Oksana A. Gavrilova Lyubov V. Rychkova Marina A. Darenskaya Lyudmila A. Grebenkina Olga V. Kravtsova Larisa V. Natyaganova
author_sort	Oksana A. Gavrilova
title	Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
title_short	Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
title_full	Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
title_fullStr	Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
title_full_unstemmed	Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis
title_sort	change of lipid peroxidation system – antioxidant protection parameters in adolescents with obesity and fatty hepatosis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/bb0031e900064ee6bff155929e129b14
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Change of Lipid Peroxidation System – Antioxidant Protection Parameters in Adolescents with Obesity and Fatty Hepatosis

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