A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1
Mapping of the HIV Env surface epitopes targeted by broadly neutralizing antibodies (bNAbs) is of great interest for HIV-1 vaccine design. Here, the authors present the 3.2 Å cryo-EM structure of the bNAb M4008_N1 in complex with BG505 DS-SOSIP, an engineered native-like Env trimer and observe that...
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Autores principales: | Kun-Wei Chan, Christina C. Luo, Hong Lu, Xueling Wu, Xiang-Peng Kong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bb01949e422e42d6906fec7ea24e7540 |
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