A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery
Delivery of siRNA to target cells is essential for in vivogene therapy. Here the authors demonstrate an oligonucleotide aptamer that targets therapeutic siRNA to a specific cell type.
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Nature Portfolio
2016
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| Acceso en línea: | https://doaj.org/article/bb078bba5219468580d803543e71575a |
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oai:doaj.org-article:bb078bba5219468580d803543e71575a2021-12-02T17:33:08ZA DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery10.1038/ncomms135802041-1723https://doaj.org/article/bb078bba5219468580d803543e71575a2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13580https://doaj.org/toc/2041-1723Delivery of siRNA to target cells is essential for in vivogene therapy. Here the authors demonstrate an oligonucleotide aptamer that targets therapeutic siRNA to a specific cell type.Kewei RenYing LiuJie WuYue ZhangJing ZhuMin YangHuangxian JuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Kewei Ren Ying Liu Jie Wu Yue Zhang Jing Zhu Min Yang Huangxian Ju A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| description |
Delivery of siRNA to target cells is essential for in vivogene therapy. Here the authors demonstrate an oligonucleotide aptamer that targets therapeutic siRNA to a specific cell type. |
| format |
article |
| author |
Kewei Ren Ying Liu Jie Wu Yue Zhang Jing Zhu Min Yang Huangxian Ju |
| author_facet |
Kewei Ren Ying Liu Jie Wu Yue Zhang Jing Zhu Min Yang Huangxian Ju |
| author_sort |
Kewei Ren |
| title |
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| title_short |
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| title_full |
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| title_fullStr |
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| title_full_unstemmed |
A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery |
| title_sort |
dna dual lock-and-key strategy for cell-subtype-specific sirna delivery |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/bb078bba5219468580d803543e71575a |
| work_keys_str_mv |
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1718380085865611264 |