Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

Non-obstructive azoospermia affects 1% of men. Here, authors perform single-cell transcriptomic analysis of human testicular cells from healthy donors and non-obstructive azoospermia patients and find that inhibition of Wnt signaling promotes the maturation of Sertoli cells from patients.

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Detalles Bibliográficos
Autores principales: LiangYu Zhao, ChenCheng Yao, XiaoYu Xing, Tao Jing, Peng Li, ZiJue Zhu, Chao Yang, Jing Zhai, RuHui Tian, HuiXing Chen, JiaQiang Luo, NaChuan Liu, ZhiWen Deng, XiaoHan Lin, Na Li, Jing Fang, Jie Sun, ChenChen Wang, Zhi Zhou, Zheng Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/bb0fbe49441045209c09d3f5a07f28af
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