Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

Non-obstructive azoospermia affects 1% of men. Here, authors perform single-cell transcriptomic analysis of human testicular cells from healthy donors and non-obstructive azoospermia patients and find that inhibition of Wnt signaling promotes the maturation of Sertoli cells from patients.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: LiangYu Zhao, ChenCheng Yao, XiaoYu Xing, Tao Jing, Peng Li, ZiJue Zhu, Chao Yang, Jing Zhai, RuHui Tian, HuiXing Chen, JiaQiang Luo, NaChuan Liu, ZhiWen Deng, XiaoHan Lin, Na Li, Jing Fang, Jie Sun, ChenChen Wang, Zhi Zhou, Zheng Li
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/bb0fbe49441045209c09d3f5a07f28af
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!