Discordancy Partitioning for Validating Potentially Inconsistent Pharmacogenomic Studies

Abstract The Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE) are two major studies that can be used to mine for therapeutic biomarkers for cancers of a large variety. Model validation using the two datasets however has proved challenging. Both predictions and s...

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Bibliographic Details
Main Authors: J. Sunil Rao, Hongmei Liu
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/bb1b8528f0514b0fbef8c0d00fe38054
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