Transmitted/Founder Hepatitis C Viruses Induce Cell-Type- and Genotype-Specific Differences in Innate Signaling within the Liver

Transmitted/Founder Hepatitis C Viruses Induce Cell-Type- and Genotype-Specific Differences in Innate Signaling within the Liver

ABSTRACT Hepatitis C virus (HCV) infection leads to persistence in the majority of cases despite triggering complex innate immune responses within the liver. Although hepatocytes are the preferred site for HCV replication, nonparenchymal cells (NPCs) can also contribute to antiviral immunity. Recent...

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Autores principales: Angela M. Mitchell, Amy E. L. Stone, Linling Cheng, Kimberly Ballinger, Michael G. Edwards, Mark Stoddard, Hui Li, Lucy Golden-Mason, George M. Shaw, Salman Khetani, Hugo R. Rosen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bb2504d3a0534ff6a5d2521177419f69
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