HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience
Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modulated through muscarinic activation of NPY+ hilar p...
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Nature Portfolio
2017
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oai:doaj.org-article:bb2ce21df8184b16927e262706f74ba52021-12-02T13:24:23ZHIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience10.1038/s41467-017-00205-32041-1723https://doaj.org/article/bb2ce21df8184b16927e262706f74ba52017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00205-3https://doaj.org/toc/2041-1723Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modulated through muscarinic activation of NPY+ hilar perforant path associated interneurons and NPY signaling in the dentate gyrus.Syed Ahsan RazaAnne AlbrechtGürsel ÇalışkanBettina MüllerYunus Emre DemiraySusann LudewigSusanne MeisNicolai FaberRoland HartigBurkhart SchravenVolkmar LessmannHerbert SchweglerOliver StorkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
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Science Q Syed Ahsan Raza Anne Albrecht Gürsel Çalışkan Bettina Müller Yunus Emre Demiray Susann Ludewig Susanne Meis Nicolai Faber Roland Hartig Burkhart Schraven Volkmar Lessmann Herbert Schwegler Oliver Stork HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
description |
Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modulated through muscarinic activation of NPY+ hilar perforant path associated interneurons and NPY signaling in the dentate gyrus. |
format |
article |
author |
Syed Ahsan Raza Anne Albrecht Gürsel Çalışkan Bettina Müller Yunus Emre Demiray Susann Ludewig Susanne Meis Nicolai Faber Roland Hartig Burkhart Schraven Volkmar Lessmann Herbert Schwegler Oliver Stork |
author_facet |
Syed Ahsan Raza Anne Albrecht Gürsel Çalışkan Bettina Müller Yunus Emre Demiray Susann Ludewig Susanne Meis Nicolai Faber Roland Hartig Burkhart Schraven Volkmar Lessmann Herbert Schwegler Oliver Stork |
author_sort |
Syed Ahsan Raza |
title |
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
title_short |
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
title_full |
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
title_fullStr |
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
title_full_unstemmed |
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
title_sort |
hipp neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5 |
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