Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy

The discovery of the first typical antipsychotics in the 1950s had revolutionized the treatment of many severe mental illnesses. This discovery opened the door for radical humanization and deinstitutionalization of the whole psychiatry. It also served as an impetus for the emergence of a new science...

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Autores principales:	Yu. V. Bykov, R. A. Bekker
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2020
Materias:	antipsychotic extrapyramidal syndrome neuroleptic-induced deficit syndrome akathisia drug-induced parkinsonism cognitive impairment electroconvulsive therapy Science Q
Acceso en línea:	https://doaj.org/article/bb2f9a9d4f104de784b2e7233a983698
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spelling	oai:doaj.org-article:bb2f9a9d4f104de784b2e7233a9836982021-11-23T06:14:44ZElectroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy2541-94202587-959610.29413/ABS.2020-5.2.9https://doaj.org/article/bb2f9a9d4f104de784b2e7233a9836982020-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2300https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The discovery of the first typical antipsychotics in the 1950s had revolutionized the treatment of many severe mental illnesses. This discovery opened the door for radical humanization and deinstitutionalization of the whole psychiatry. It also served as an impetus for the emergence of a new science, called psychopharmacology. This signaled the beginning of an era of widespread use of psychopharmacotherapy in psychiatry. However, the use of typical antipsychotics has been associated with many side effects, including severe ones, such as severe extrapyramidal syndrome, neuroleptic-induced deficit syndrome, cognitive impairment, and neuroleptic malignant syndrome. This necessitated the development of methods for correction or treatment of such side effects.Over the past decades, a number of new antipsychotics have been synthesised and approved for clinical use. Those new drugs are considered to belong to the group of so-called «atypical antipsychotics». This group, as a whole, has an improved tolerance and safety profile compared to older, conventional antipsychotics. In particular, these new drugs less often cause exactly the aforementioned side effects. Nevertheless, the problem of antipsychotic side effects and their correction is still far from being resolved. Some patients experiencing certain side effects from antipsychotic therapy do not get adequate relief from the standard pharmacological correction of those side effects.This fact stimulated our interest in the study of the possibilities of using electroconvulsive therapy as an alternative or adjuvant method for the correction of some side effects that can arise during antipsychotic therapy. In this article, we thoroughly discuss the existing evidence base regarding the effectiveness and safety of the use of electroconvulsive therapy as a corrector for certain side effects that can occur during antipsychotic therapy.Yu. V. BykovR. A. BekkerScientific Сentre for Family Health and Human Reproduction Problemsarticleantipsychoticextrapyramidal syndromeneuroleptic-induced deficit syndromeakathisiadrug-induced parkinsonismcognitive impairmentelectroconvulsive therapyScienceQRUActa Biomedica Scientifica, Vol 5, Iss 2, Pp 55-82 (2020)
institution	DOAJ
collection	DOAJ
language	RU
topic	antipsychotic extrapyramidal syndrome neuroleptic-induced deficit syndrome akathisia drug-induced parkinsonism cognitive impairment electroconvulsive therapy Science Q
spellingShingle	antipsychotic extrapyramidal syndrome neuroleptic-induced deficit syndrome akathisia drug-induced parkinsonism cognitive impairment electroconvulsive therapy Science Q Yu. V. Bykov R. A. Bekker Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
description	The discovery of the first typical antipsychotics in the 1950s had revolutionized the treatment of many severe mental illnesses. This discovery opened the door for radical humanization and deinstitutionalization of the whole psychiatry. It also served as an impetus for the emergence of a new science, called psychopharmacology. This signaled the beginning of an era of widespread use of psychopharmacotherapy in psychiatry. However, the use of typical antipsychotics has been associated with many side effects, including severe ones, such as severe extrapyramidal syndrome, neuroleptic-induced deficit syndrome, cognitive impairment, and neuroleptic malignant syndrome. This necessitated the development of methods for correction or treatment of such side effects.Over the past decades, a number of new antipsychotics have been synthesised and approved for clinical use. Those new drugs are considered to belong to the group of so-called «atypical antipsychotics». This group, as a whole, has an improved tolerance and safety profile compared to older, conventional antipsychotics. In particular, these new drugs less often cause exactly the aforementioned side effects. Nevertheless, the problem of antipsychotic side effects and their correction is still far from being resolved. Some patients experiencing certain side effects from antipsychotic therapy do not get adequate relief from the standard pharmacological correction of those side effects.This fact stimulated our interest in the study of the possibilities of using electroconvulsive therapy as an alternative or adjuvant method for the correction of some side effects that can arise during antipsychotic therapy. In this article, we thoroughly discuss the existing evidence base regarding the effectiveness and safety of the use of electroconvulsive therapy as a corrector for certain side effects that can occur during antipsychotic therapy.
format	article
author	Yu. V. Bykov R. A. Bekker
author_facet	Yu. V. Bykov R. A. Bekker
author_sort	Yu. V. Bykov
title	Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
title_short	Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
title_full	Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
title_fullStr	Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
title_full_unstemmed	Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy
title_sort	electroconvulsive therapy as a corrector for certain side effects of antipsychotic therapy
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2020
url	https://doaj.org/article/bb2f9a9d4f104de784b2e7233a983698
work_keys_str_mv	AT yuvbykov electroconvulsivetherapyasacorrectorforcertainsideeffectsofantipsychotictherapy AT rabekker electroconvulsivetherapyasacorrectorforcertainsideeffectsofantipsychotictherapy
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Electroconvulsive Therapy as a Corrector for Certain Side Effects of Antipsychotic Therapy

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