Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins

In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE. Here the authors present cryo-EM structures of nanodisc-embedded LolCDE in different states, providing mechanistic insight into the tr...

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Autores principales:	Stuti Sharma, Ruoyu Zhou, Li Wan, Shan Feng, KangKang Song, Chen Xu, Yanyan Li, Maofu Liao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bb2fc5fe97904f1d8ba8289605946e21
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spelling	oai:doaj.org-article:bb2fc5fe97904f1d8ba8289605946e212021-12-02T16:35:42ZMechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins10.1038/s41467-021-24965-12041-1723https://doaj.org/article/bb2fc5fe97904f1d8ba8289605946e212021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24965-1https://doaj.org/toc/2041-1723In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE. Here the authors present cryo-EM structures of nanodisc-embedded LolCDE in different states, providing mechanistic insight into the transport mechanism.Stuti SharmaRuoyu ZhouLi WanShan FengKangKang SongChen XuYanyan LiMaofu LiaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stuti Sharma Ruoyu Zhou Li Wan Shan Feng KangKang Song Chen Xu Yanyan Li Maofu Liao Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
description	In Gram-negative bacteria, lipoproteins are transported from the inner membrane (IM) to the outer membrane (OM) by the ATP-binding cassette (ABC) transporter LolCDE. Here the authors present cryo-EM structures of nanodisc-embedded LolCDE in different states, providing mechanistic insight into the transport mechanism.
format	article
author	Stuti Sharma Ruoyu Zhou Li Wan Shan Feng KangKang Song Chen Xu Yanyan Li Maofu Liao
author_facet	Stuti Sharma Ruoyu Zhou Li Wan Shan Feng KangKang Song Chen Xu Yanyan Li Maofu Liao
author_sort	Stuti Sharma
title	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
title_short	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
title_full	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
title_fullStr	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
title_full_unstemmed	Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
title_sort	mechanism of lolcde as a molecular extruder of bacterial triacylated lipoproteins
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bb2fc5fe97904f1d8ba8289605946e21
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Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins

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