Familial Mediterranean fever-related miR-197-3p targets IL1R1 gene and modulates inflammation in monocytes and synovial fibroblasts

Abstract Familial Mediterranean fever (FMF); is an autosomal recessively inherited autoinflammatory disease caused by the mutations in the Mediterranean Fever (MEFV) gene. Recent studies have shown that epigenetic control mechanisms, particularly non-coding RNAs, may play a role in the pathogenesis...

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Autores principales: Yeliz Z. Akkaya-Ulum, Tayfun Hilmi Akbaba, Zeynep Tavukcuoglu, Jae Jin Chae, Engin Yilmaz, Seza Ozen, Banu Balci-Peynircioglu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bb33032f28b04874b0a8409ccf3ecf90
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