Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations

Leptospirosis is a cosmopolitan natural-focal disease representing a serious problem for the majority of the countries in the world including the Russian Federation because this infection causes a serious economic and social damage. Modern laboratory diagnostics of leptospiroses is based on a comple...

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Autores principales:	Ye. Yu. Kiseleva, N. V. Breneva, A. K. Noskov, M. B. Sharakshanov, S. V. Balakhonov, N. G. Gefan
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	leptospirosis laboratory diagnostics Science Q
Acceso en línea:	https://doaj.org/article/bb34f79bac634005b6a907a5e8904f38
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spelling	oai:doaj.org-article:bb34f79bac634005b6a907a5e8904f382021-11-23T06:14:32ZMethods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations2541-94202587-9596https://doaj.org/article/bb34f79bac634005b6a907a5e8904f382015-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/77https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Leptospirosis is a cosmopolitan natural-focal disease representing a serious problem for the majority of the countries in the world including the Russian Federation because this infection causes a serious economic and social damage. Modern laboratory diagnostics of leptospiroses is based on a complex of bacteriological, immunological and molecularbiological methods used in various combinations depending on the problems and possibilities of the laboratories. At all variety, many methods are not applied in practice and the gold standard still remains the routine serological method. Disease diagnostics is based on a set of epidemiological, epizootological, clinical and pathoanatomical data with obligatory laboratory verification of the diagnosis. However often laboratory verification is retrospective or in general absent. For achievement of the best results in leptospirosis diagnostics, it is necessary to improve the available laboratory methods and to use it in practice. Especial attention should be given to introduction of new molecular technologies that simplify laboratory diagnostics and expand its possibilities.Ye. Yu. KiselevaN. V. BrenevaA. K. NoskovM. B. SharakshanovS. V. BalakhonovN. G. GefanScientific Сentre for Family Health and Human Reproduction Problemsarticleleptospirosislaboratory diagnosticsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3, Pp 85-93 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	leptospirosis laboratory diagnostics Science Q
spellingShingle	leptospirosis laboratory diagnostics Science Q Ye. Yu. Kiseleva N. V. Breneva A. K. Noskov M. B. Sharakshanov S. V. Balakhonov N. G. Gefan Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
description	Leptospirosis is a cosmopolitan natural-focal disease representing a serious problem for the majority of the countries in the world including the Russian Federation because this infection causes a serious economic and social damage. Modern laboratory diagnostics of leptospiroses is based on a complex of bacteriological, immunological and molecularbiological methods used in various combinations depending on the problems and possibilities of the laboratories. At all variety, many methods are not applied in practice and the gold standard still remains the routine serological method. Disease diagnostics is based on a set of epidemiological, epizootological, clinical and pathoanatomical data with obligatory laboratory verification of the diagnosis. However often laboratory verification is retrospective or in general absent. For achievement of the best results in leptospirosis diagnostics, it is necessary to improve the available laboratory methods and to use it in practice. Especial attention should be given to introduction of new molecular technologies that simplify laboratory diagnostics and expand its possibilities.
format	article
author	Ye. Yu. Kiseleva N. V. Breneva A. K. Noskov M. B. Sharakshanov S. V. Balakhonov N. G. Gefan
author_facet	Ye. Yu. Kiseleva N. V. Breneva A. K. Noskov M. B. Sharakshanov S. V. Balakhonov N. G. Gefan
author_sort	Ye. Yu. Kiseleva
title	Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
title_short	Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
title_full	Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
title_fullStr	Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
title_full_unstemmed	Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
title_sort	methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/bb34f79bac634005b6a907a5e8904f38
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Methods for leptospirosis laboratory diagnostics: features of experimentation, advantages and limitations

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