Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore

Abstract The population is rapidly aging worldwide, and there is an age-related decline in muscle mass. Therefore, it is important to examine the prevalence and associated factors of low appendicular skeletal muscle mass index (ASMI) in older adults. The objectives of this cross-sectional study were...

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Autores principales:	Siew Ling Tey, Dieu Thi Thu Huynh, Yatin Berde, Geraldine Baggs, Choon How How, Yen Ling Low, Magdalin Cheong, Wai Leng Chow, Ngiap Chuan Tan, Samuel Teong Huang Chew
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bb3872072b53437bbe050bc09a495d51
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spelling	oai:doaj.org-article:bb3872072b53437bbe050bc09a495d512021-12-05T12:15:16ZPrevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore10.1038/s41598-021-02274-32045-2322https://doaj.org/article/bb3872072b53437bbe050bc09a495d512021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02274-3https://doaj.org/toc/2045-2322Abstract The population is rapidly aging worldwide, and there is an age-related decline in muscle mass. Therefore, it is important to examine the prevalence and associated factors of low appendicular skeletal muscle mass index (ASMI) in older adults. The objectives of this cross-sectional study were (i) to determine the prevalence of low ASMI (ASM/height2) and (ii) to identify factors associated with low ASMI. This study included 1211 community-dwelling adults aged ≥ 65 years. Low ASMI was defined as < 7.0 kg/m2 in males and < 5.7 kg/m2 in females (bioelectrical impedance analysis). Gender-specific cut-off values of calf circumference for low ASMI were determined. The prevalence of low ASMI in the overall cohort was 59.9%, i.e., 57.0% among males and 61.8% among females, with no significant difference between genders (P = 0.1068). The prevalence of low ASMI was 81.3% in individuals at risk of malnutrition compared to 20.6% in their counterparts with normal nutritional status (P < 0.0001). Participants with low ASMI were older, had lower physical activity scores, and greater likelihood of hospitalization in prior 6 months compared with normal ASMI (all P < 0.0001). Low ASMI was associated with risk of malnutrition (odds ratio: 3.58 for medium risk, odds ratio: 12.50 for high risk), older age, smoking, drinking, smaller calf circumference, and lower bone mass (all P ≤ 0.0328). Cut-off values of calf circumference for low ASMI for males was 33.4 cm and for females was 32.2 cm. In conclusion, we found that low ASMI was highly prevalent among community-dwelling older adults at risk of malnutrition. Other significant factors associated with low ASMI were age, smoking, drinking, calf circumference, and bone mass. Screening community-dwelling older adults for risk of malnutrition can prevent or delay onset of low ASMI.Siew Ling TeyDieu Thi Thu HuynhYatin BerdeGeraldine BaggsChoon How HowYen Ling LowMagdalin CheongWai Leng ChowNgiap Chuan TanSamuel Teong Huang ChewNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Siew Ling Tey Dieu Thi Thu Huynh Yatin Berde Geraldine Baggs Choon How How Yen Ling Low Magdalin Cheong Wai Leng Chow Ngiap Chuan Tan Samuel Teong Huang Chew Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
description	Abstract The population is rapidly aging worldwide, and there is an age-related decline in muscle mass. Therefore, it is important to examine the prevalence and associated factors of low appendicular skeletal muscle mass index (ASMI) in older adults. The objectives of this cross-sectional study were (i) to determine the prevalence of low ASMI (ASM/height2) and (ii) to identify factors associated with low ASMI. This study included 1211 community-dwelling adults aged ≥ 65 years. Low ASMI was defined as < 7.0 kg/m2 in males and < 5.7 kg/m2 in females (bioelectrical impedance analysis). Gender-specific cut-off values of calf circumference for low ASMI were determined. The prevalence of low ASMI in the overall cohort was 59.9%, i.e., 57.0% among males and 61.8% among females, with no significant difference between genders (P = 0.1068). The prevalence of low ASMI was 81.3% in individuals at risk of malnutrition compared to 20.6% in their counterparts with normal nutritional status (P < 0.0001). Participants with low ASMI were older, had lower physical activity scores, and greater likelihood of hospitalization in prior 6 months compared with normal ASMI (all P < 0.0001). Low ASMI was associated with risk of malnutrition (odds ratio: 3.58 for medium risk, odds ratio: 12.50 for high risk), older age, smoking, drinking, smaller calf circumference, and lower bone mass (all P ≤ 0.0328). Cut-off values of calf circumference for low ASMI for males was 33.4 cm and for females was 32.2 cm. In conclusion, we found that low ASMI was highly prevalent among community-dwelling older adults at risk of malnutrition. Other significant factors associated with low ASMI were age, smoking, drinking, calf circumference, and bone mass. Screening community-dwelling older adults for risk of malnutrition can prevent or delay onset of low ASMI.
format	article
author	Siew Ling Tey Dieu Thi Thu Huynh Yatin Berde Geraldine Baggs Choon How How Yen Ling Low Magdalin Cheong Wai Leng Chow Ngiap Chuan Tan Samuel Teong Huang Chew
author_facet	Siew Ling Tey Dieu Thi Thu Huynh Yatin Berde Geraldine Baggs Choon How How Yen Ling Low Magdalin Cheong Wai Leng Chow Ngiap Chuan Tan Samuel Teong Huang Chew
author_sort	Siew Ling Tey
title	Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
title_short	Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
title_full	Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
title_fullStr	Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
title_full_unstemmed	Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore
title_sort	prevalence of low muscle mass and associated factors in community-dwelling older adults in singapore
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bb3872072b53437bbe050bc09a495d51
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Prevalence of low muscle mass and associated factors in community-dwelling older adults in Singapore

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