The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.

The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.

Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli for DNA repair initiation at deaminated adenine is endonuclease V (endoV), encoded by the nfi gene, which cleaves the second phosphodiester...

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Autores principales: Cathrine Fladeby, Erik Sebastian Vik, Jon K Laerdahl, Christine Gran Neurauter, Julie E Heggelund, Eirik Thorgaard, Pernille Strøm-Andersen, Magnar Bjørås, Bjørn Dalhus, Ingrun Alseth
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bb426f79ed904e0cb7f206bd3e15855d
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