Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite

VV Anusha Thampi,1 P Dhandapani,2 Geetha Manivasagam, B Subramanian11Electrochemical Materials Science Division, Central Electrochemical Research Institute, Karaikudi, 2Corrosion and Materials Protection Division, Central Electrochemical Reserach Institute, Karaikudi, 3Centre for Bio-Materials Scien...

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Autores principales:	Thampi VV, Dhandapani P, Manivasagam G, Subramanian B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bb553b62eac24896811a8af7a7176675
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spelling	oai:doaj.org-article:bb553b62eac24896811a8af7a71766752021-12-02T02:11:14ZEnhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite1178-2013https://doaj.org/article/bb553b62eac24896811a8af7a71766752015-10-01T00:00:00Zhttps://www.dovepress.com/enhancement-of-bioactivity-of-titanium-carbonitride-nanocomposite-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013VV Anusha Thampi,1 P Dhandapani,2 Geetha Manivasagam, B Subramanian11Electrochemical Materials Science Division, Central Electrochemical Research Institute, Karaikudi, 2Corrosion and Materials Protection Division, Central Electrochemical Reserach Institute, Karaikudi, 3Centre for Bio-Materials Science and Technology, VIT University, Vellore, IndiaAbstract: Thin films of titanium carbonitride (TiCN) were fabricated by DC magnetron sputtering on medical grade steel. The biocompatibility of the coating was further enhanced by growing hydroxyapatite crystals over the TiCN-coated substrates using biologically activated ammonia from synthetic urine. The coatings were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy (SEM)-energy dispersive spectroscopy, and Raman spectroscopy. The electrochemical behavior of the coatings was determined in simulated body fluid. In addition, hemocompatibility was assessed by monitoring the attachment of platelets on the coating using SEM. The wettability of the coatings was measured in order to correlate with biocompatibility results. Formation of a coating with granular morphology and the preferred orientation was confirmed by SEM and X-ray diffraction results. The hydroxyapatite coating led to a decrease in thrombogenicity, resulting in controlled blood clot formation, hence demonstrating the hemocompatibility of the coating.Keywords: titanium carbonitride thin films, magnetron sputtering, ureolytic bacteria, biocompatibilityThampi VVDhandapani PManivasagam GSubramanian BDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss Supplement 1 Challenges in biomaterials research, Pp 107-118 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Thampi VV Dhandapani P Manivasagam G Subramanian B Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
description	VV Anusha Thampi,1 P Dhandapani,2 Geetha Manivasagam, B Subramanian11Electrochemical Materials Science Division, Central Electrochemical Research Institute, Karaikudi, 2Corrosion and Materials Protection Division, Central Electrochemical Reserach Institute, Karaikudi, 3Centre for Bio-Materials Science and Technology, VIT University, Vellore, IndiaAbstract: Thin films of titanium carbonitride (TiCN) were fabricated by DC magnetron sputtering on medical grade steel. The biocompatibility of the coating was further enhanced by growing hydroxyapatite crystals over the TiCN-coated substrates using biologically activated ammonia from synthetic urine. The coatings were characterized using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy (SEM)-energy dispersive spectroscopy, and Raman spectroscopy. The electrochemical behavior of the coatings was determined in simulated body fluid. In addition, hemocompatibility was assessed by monitoring the attachment of platelets on the coating using SEM. The wettability of the coatings was measured in order to correlate with biocompatibility results. Formation of a coating with granular morphology and the preferred orientation was confirmed by SEM and X-ray diffraction results. The hydroxyapatite coating led to a decrease in thrombogenicity, resulting in controlled blood clot formation, hence demonstrating the hemocompatibility of the coating.Keywords: titanium carbonitride thin films, magnetron sputtering, ureolytic bacteria, biocompatibility
format	article
author	Thampi VV Dhandapani P Manivasagam G Subramanian B
author_facet	Thampi VV Dhandapani P Manivasagam G Subramanian B
author_sort	Thampi VV
title	Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
title_short	Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
title_full	Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
title_fullStr	Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
title_full_unstemmed	Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
title_sort	enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/bb553b62eac24896811a8af7a7176675
work_keys_str_mv	AT thampivv enhancementofbioactivityoftitaniumcarbonitridenanocompositethinfilmsonsteelswithbiosynthesizedhydroxyapatite AT dhandapanip enhancementofbioactivityoftitaniumcarbonitridenanocompositethinfilmsonsteelswithbiosynthesizedhydroxyapatite AT manivasagamg enhancementofbioactivityoftitaniumcarbonitridenanocompositethinfilmsonsteelswithbiosynthesizedhydroxyapatite AT subramanianb enhancementofbioactivityoftitaniumcarbonitridenanocompositethinfilmsonsteelswithbiosynthesizedhydroxyapatite
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Enhancement of bioactivity of titanium carbonitride nanocomposite thin films on steels with biosynthesized hydroxyapatite

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