Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities

Saeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Put...

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Autores principales:	Ebrahimiasl S, Zakaria A, Kassim A, Basri SN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bb56ef24ff6e4b068454d0b6f24d6131
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spelling	oai:doaj.org-article:bb56ef24ff6e4b068454d0b6f24d61312021-12-02T00:31:22ZNovel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities1178-2013https://doaj.org/article/bb56ef24ff6e4b068454d0b6f24d61312014-12-01T00:00:00Zhttp://www.dovepress.com/novel-conductive-polypyrrolezinc-oxidechitosan-bionanocomposite-synthe-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Saeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Putra Malaysia, Serdang, Malaysia; 4Department of Chemistry, Universiti Putra Malaysia, Serdang, Malaysia Abstract: An antibacterial and conductive bionanocomposite (BNC) film consisting of polypyrrole (Ppy), zinc oxide (ZnO) nanoparticles (NPs), and chitosan (CS) was electrochemically synthesized on indium tin oxide (ITO) glass substrate by electrooxidation of 0.1 M pyrrole in aqueous solution containing appropriate amounts of ZnO NPs uniformly dispersed in CS. This method enables the room temperature electrosynthesis of BNC film consisting of ZnO NPs incorporated within the growing Ppy/CS composite. The morphology of Ppy/ZnO/CS BNC was characterized by scanning electron microscopy. ITO–Ppy/CS and ITO–Ppy/ZnO/CS bioelectrodes were characterized using the Fourier transform infrared technique, X-ray diffraction, and thermogravimetric analysis. The electrical conductivity of nanocomposites was investigated by a four-probe method. The prepared nanocomposites were analyzed for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl assay. The results demonstrated that the antioxidant activity of nanocomposites increased remarkably by addition of ZnO NPs. The electrical conductivity of films showed a sudden decrease for lower weight ratios of ZnO NPs (5 wt%), while it was increased gradually for higher ratios (10, 15, and 20 wt%). The nanocomposites were analyzed for antibacterial activity against Gram-positive and Gram-negative bacteria. The results indicated that the synthesized BNC is effective against all of the studied bacteria, and its effectiveness is higher for Pseudomonas aeruginosa. The thermal stability and physical properties of BNC films were increased by an increase in the weight ratio of ZnO NPs, promising novel applications for the electrically conductive polysaccharide-based nanocomposites, particularly those that may exploit the antimicrobial nature of Ppy/ZnO/CS BNCs. Keywords: bionanocomposite, electrodeposition, conductive, antibacterial, antioxidantEbrahimiasl SZakaria AKassim ABasri SNDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 217-227 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Ebrahimiasl S Zakaria A Kassim A Basri SN Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
description	Saeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Putra Malaysia, Serdang, Malaysia; 4Department of Chemistry, Universiti Putra Malaysia, Serdang, Malaysia Abstract: An antibacterial and conductive bionanocomposite (BNC) film consisting of polypyrrole (Ppy), zinc oxide (ZnO) nanoparticles (NPs), and chitosan (CS) was electrochemically synthesized on indium tin oxide (ITO) glass substrate by electrooxidation of 0.1 M pyrrole in aqueous solution containing appropriate amounts of ZnO NPs uniformly dispersed in CS. This method enables the room temperature electrosynthesis of BNC film consisting of ZnO NPs incorporated within the growing Ppy/CS composite. The morphology of Ppy/ZnO/CS BNC was characterized by scanning electron microscopy. ITO–Ppy/CS and ITO–Ppy/ZnO/CS bioelectrodes were characterized using the Fourier transform infrared technique, X-ray diffraction, and thermogravimetric analysis. The electrical conductivity of nanocomposites was investigated by a four-probe method. The prepared nanocomposites were analyzed for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl assay. The results demonstrated that the antioxidant activity of nanocomposites increased remarkably by addition of ZnO NPs. The electrical conductivity of films showed a sudden decrease for lower weight ratios of ZnO NPs (5 wt%), while it was increased gradually for higher ratios (10, 15, and 20 wt%). The nanocomposites were analyzed for antibacterial activity against Gram-positive and Gram-negative bacteria. The results indicated that the synthesized BNC is effective against all of the studied bacteria, and its effectiveness is higher for Pseudomonas aeruginosa. The thermal stability and physical properties of BNC films were increased by an increase in the weight ratio of ZnO NPs, promising novel applications for the electrically conductive polysaccharide-based nanocomposites, particularly those that may exploit the antimicrobial nature of Ppy/ZnO/CS BNCs. Keywords: bionanocomposite, electrodeposition, conductive, antibacterial, antioxidant
format	article
author	Ebrahimiasl S Zakaria A Kassim A Basri SN
author_facet	Ebrahimiasl S Zakaria A Kassim A Basri SN
author_sort	Ebrahimiasl S
title	Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
title_short	Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
title_full	Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
title_fullStr	Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
title_full_unstemmed	Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
title_sort	novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/bb56ef24ff6e4b068454d0b6f24d6131
work_keys_str_mv	AT ebrahimiasls novelconductivepolypyrrolezincoxidechitosanbionanocompositesynthesischaracterizationantioxidantandantibacterialactivities AT zakariaa novelconductivepolypyrrolezincoxidechitosanbionanocompositesynthesischaracterizationantioxidantandantibacterialactivities AT kassima novelconductivepolypyrrolezincoxidechitosanbionanocompositesynthesischaracterizationantioxidantandantibacterialactivities AT basrisn novelconductivepolypyrrolezincoxidechitosanbionanocompositesynthesischaracterizationantioxidantandantibacterialactivities
_version_	1718403702922936320

Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities

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