Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells

Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells

Abstract The ability of isolated neural stem cells (NSCs) to proliferate as neurospheres is indicative of their competence as stem cells, and depends critically on the polycomb group (PcG) member Bmi1: knockdown of Bmi1 results in defective proliferation and self-renewal of isolated NSCs, whereas ov...

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Autores principales: Mythily Ganapathi, Nathan C. Boles, Carol Charniga, Steven Lotz, Melissa Campbell, Sally Temple, Randall H. Morse
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/bb6451d396854ca396639407b1055802
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