Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex
ClpXP is the main ATP-dependent proteolytic complex in bacteria, is essential for maintaining cellular protein homeostasis and is also critical for bacterial pathogenesis. Here, the authors establish a functional link between ClpXP and trigger actor, a chaperone involved in the early stages of prote...
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Nature Portfolio
2021
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oai:doaj.org-article:bb669bad02bc48fc84564ad9819545992021-12-02T15:22:39ZFunctional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex10.1038/s41467-020-20553-x2041-1723https://doaj.org/article/bb669bad02bc48fc84564ad9819545992021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20553-xhttps://doaj.org/toc/2041-1723ClpXP is the main ATP-dependent proteolytic complex in bacteria, is essential for maintaining cellular protein homeostasis and is also critical for bacterial pathogenesis. Here, the authors establish a functional link between ClpXP and trigger actor, a chaperone involved in the early stages of protein folding.Kamran RizzoloAngela Yeou Hsiung YuAdedeji OlogbenlaSa-Rang KimHaojie ZhuKoichiro IshimoriGuillaume ThibaultElisa LeungYi Wen ZhangMona TengMarta HaniszewskiNoha MiahSadhna PhanseZoran MinicSukyeong LeeJulio Diaz CaballeroMohan BabuFrancis T. F. TsaiTomohide SaioWalid A. HouryNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
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Science Q Kamran Rizzolo Angela Yeou Hsiung Yu Adedeji Ologbenla Sa-Rang Kim Haojie Zhu Koichiro Ishimori Guillaume Thibault Elisa Leung Yi Wen Zhang Mona Teng Marta Haniszewski Noha Miah Sadhna Phanse Zoran Minic Sukyeong Lee Julio Diaz Caballero Mohan Babu Francis T. F. Tsai Tomohide Saio Walid A. Houry Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
description |
ClpXP is the main ATP-dependent proteolytic complex in bacteria, is essential for maintaining cellular protein homeostasis and is also critical for bacterial pathogenesis. Here, the authors establish a functional link between ClpXP and trigger actor, a chaperone involved in the early stages of protein folding. |
format |
article |
author |
Kamran Rizzolo Angela Yeou Hsiung Yu Adedeji Ologbenla Sa-Rang Kim Haojie Zhu Koichiro Ishimori Guillaume Thibault Elisa Leung Yi Wen Zhang Mona Teng Marta Haniszewski Noha Miah Sadhna Phanse Zoran Minic Sukyeong Lee Julio Diaz Caballero Mohan Babu Francis T. F. Tsai Tomohide Saio Walid A. Houry |
author_facet |
Kamran Rizzolo Angela Yeou Hsiung Yu Adedeji Ologbenla Sa-Rang Kim Haojie Zhu Koichiro Ishimori Guillaume Thibault Elisa Leung Yi Wen Zhang Mona Teng Marta Haniszewski Noha Miah Sadhna Phanse Zoran Minic Sukyeong Lee Julio Diaz Caballero Mohan Babu Francis T. F. Tsai Tomohide Saio Walid A. Houry |
author_sort |
Kamran Rizzolo |
title |
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
title_short |
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
title_full |
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
title_fullStr |
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
title_full_unstemmed |
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex |
title_sort |
functional cooperativity between the trigger factor chaperone and the clpxp proteolytic complex |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bb669bad02bc48fc84564ad981954599 |
work_keys_str_mv |
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1718387399145291776 |