Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19

Abstract: SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan, China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal and cardiac diagnostic markers in hospital in patients with severe COVID 19. In this study, 259 patients wi...

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Autor principal:	Esmat Radmanesh
Formato:	article
Lenguaje:	EN
Publicado:	Tehran University of Medical Sciences 2021
Materias:	diagnostic markers covid 19 abadan Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bb7b1b124c924088a503760f974053d6
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spelling	oai:doaj.org-article:bb7b1b124c924088a503760f974053d62021-11-29T06:16:21ZEvaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 190044-60251735-969410.18502/acta.v59i11.7778https://doaj.org/article/bb7b1b124c924088a503760f974053d62021-11-01T00:00:00Zhttps://acta.tums.ac.ir/index.php/acta/article/view/9175https://doaj.org/toc/0044-6025https://doaj.org/toc/1735-9694Abstract: SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan, China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal and cardiac diagnostic markers in hospital in patients with severe COVID 19. In this study, 259 patients with symptoms of severe COVID-19 and a positive RT-PCR assay of nasopharyngeal samples were enrolled. Inclusion criteria are positive for COVID-19 patients at the diagnosis of an infectious disease physician. Diagnostic markers of liver, kidney, and heart, were evaluated by age and gender. In this study, 48.3% of patients severe with COVID- 19 were male and 51.7% were female. The mean of markers such as LDH, Direct Bilirubin, SGOT, SGPT, D-dimer, was higher than normal, which was observed in men more than women. The mean of CK-MB also was higher than normal, which was observed in women more than men. The highest mean of markers was seen in the older ages. The mean of BUN was observed in the age range of 55-64 years and above 65 years above normal. But the mean of CPK, creatinine, potassium, and alkaline phosphatase were normal. The results of the present study showed an increase in the level of some of the most important diagnostic markers of hepatic, renal, and cardiac in patients with COVID 19. This increase was greater in some markers, including SGOT, SGPT, Direct bilirubin, LDH, D-dimer, in men than in women, and more in older patients.Esmat RadmaneshTehran University of Medical Sciencesarticlediagnostic markerscovid 19abadanMedicine (General)R5-920ENActa Medica Iranica, Pp 656-661 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	diagnostic markers covid 19 abadan Medicine (General) R5-920
spellingShingle	diagnostic markers covid 19 abadan Medicine (General) R5-920 Esmat Radmanesh Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
description	Abstract: SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan, China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal and cardiac diagnostic markers in hospital in patients with severe COVID 19. In this study, 259 patients with symptoms of severe COVID-19 and a positive RT-PCR assay of nasopharyngeal samples were enrolled. Inclusion criteria are positive for COVID-19 patients at the diagnosis of an infectious disease physician. Diagnostic markers of liver, kidney, and heart, were evaluated by age and gender. In this study, 48.3% of patients severe with COVID- 19 were male and 51.7% were female. The mean of markers such as LDH, Direct Bilirubin, SGOT, SGPT, D-dimer, was higher than normal, which was observed in men more than women. The mean of CK-MB also was higher than normal, which was observed in women more than men. The highest mean of markers was seen in the older ages. The mean of BUN was observed in the age range of 55-64 years and above 65 years above normal. But the mean of CPK, creatinine, potassium, and alkaline phosphatase were normal. The results of the present study showed an increase in the level of some of the most important diagnostic markers of hepatic, renal, and cardiac in patients with COVID 19. This increase was greater in some markers, including SGOT, SGPT, Direct bilirubin, LDH, D-dimer, in men than in women, and more in older patients.
format	article
author	Esmat Radmanesh
author_facet	Esmat Radmanesh
author_sort	Esmat Radmanesh
title	Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
title_short	Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
title_full	Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
title_fullStr	Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
title_full_unstemmed	Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19
title_sort	evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with covid- 19
publisher	Tehran University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/bb7b1b124c924088a503760f974053d6
work_keys_str_mv	AT esmatradmanesh evaluationofhepaticrenalandcardiacdiagnosticmarkersinpatientsseverewithcovid19
_version_	1718407609929695232

Evaluation of hepatic, renal and cardiac diagnostic markers in patients severe with COVID- 19

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