Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina

Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina

Summary: Gene regulatory networks (GRNs), consisting of transcription factors and their target sites, control neurogenesis and cell-fate specification in the developing central nervous system. In this study, we use integrated single-cell RNA and single-cell ATAC sequencing (scATAC-seq) analysis in d...

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Detalles Bibliográficos
Autores principales: Pin Lyu, Thanh Hoang, Clayton P. Santiago, Eric D. Thomas, Andrew E. Timms, Haley Appel, Megan Gimmen, Nguyet Le, Lizhi Jiang, Dong Won Kim, Siqi Chen, David F. Espinoza, Ariel E. Telger, Kurt Weir, Brian S. Clark, Timothy J. Cherry, Jiang Qian, Seth Blackshaw
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
retina
development
transcription factor
neurogenesis
single-cell ATAC-seq
single-cell RNA-seq
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/bb845b0091334d5fbe14f15fb9a4f379
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