Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

Bacterial beta-lactamases are responsible for resistance to beta-lactams, the most important family of antibiotics. Here, the authors reveal cyclic boronate inhibitors that are active against both serine- and metallo-beta-lactamases and represent a promising strategy for combined antimicrobial treat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jürgen Brem, Ricky Cain, Samuel Cahill, Michael A. McDonough, Ian J. Clifton, Juan-Carlos Jiménez-Castellanos, Matthew B. Avison, James Spencer, Colin W. G. Fishwick, Christopher J. Schofield
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/bb894e352b404c67a6c95bd78e1a12a8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares