Recognition of Chiral Carboxylates by Synthetic Receptors

Recognition of anionic species plays a fundamental role in many essential chemical, biological, and environmental processes. Numerous monographs and review papers on molecular recognition of anions by synthetic receptors reflect the continuing and growing interest in this area of supramolecular chem...

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Autores principales: Patryk Niedbała, Kajetan Dąbrowa, Sylwia Wasiłek, Janusz Jurczak
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:bb900298cbb04588b1bf48fee3dbd28e2021-11-11T18:26:07ZRecognition of Chiral Carboxylates by Synthetic Receptors10.3390/molecules262164171420-3049https://doaj.org/article/bb900298cbb04588b1bf48fee3dbd28e2021-10-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6417https://doaj.org/toc/1420-3049Recognition of anionic species plays a fundamental role in many essential chemical, biological, and environmental processes. Numerous monographs and review papers on molecular recognition of anions by synthetic receptors reflect the continuing and growing interest in this area of supramolecular chemistry. However, despite the enormous progress made over the last 20 years in the design of these molecules, the design of receptors for chiral anions is much less developed. Chiral recognition is one of the most subtle types of selectivity, and it requires very precise spatial organization of the receptor framework. At the same time, this phenomenon commonly occurs in many processes present in nature, often being their fundamental step. For these reasons, research directed toward understanding the chiral anion recognition phenomenon may lead to the identification of structural patterns that enable increasingly efficient receptor design. In this review, we present the recent progress made in the area of synthetic receptors for biologically relevant chiral carboxylates.Patryk NiedbałaKajetan DąbrowaSylwia WasiłekJanusz JurczakMDPI AGarticlesupramolecular chemistryanion recognitionchiral recognitioncarboxylatessynthetic receptorsOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6417, p 6417 (2021)
institution DOAJ
collection DOAJ
language EN
topic supramolecular chemistry
anion recognition
chiral recognition
carboxylates
synthetic receptors
Organic chemistry
QD241-441
spellingShingle supramolecular chemistry
anion recognition
chiral recognition
carboxylates
synthetic receptors
Organic chemistry
QD241-441
Patryk Niedbała
Kajetan Dąbrowa
Sylwia Wasiłek
Janusz Jurczak
Recognition of Chiral Carboxylates by Synthetic Receptors
description Recognition of anionic species plays a fundamental role in many essential chemical, biological, and environmental processes. Numerous monographs and review papers on molecular recognition of anions by synthetic receptors reflect the continuing and growing interest in this area of supramolecular chemistry. However, despite the enormous progress made over the last 20 years in the design of these molecules, the design of receptors for chiral anions is much less developed. Chiral recognition is one of the most subtle types of selectivity, and it requires very precise spatial organization of the receptor framework. At the same time, this phenomenon commonly occurs in many processes present in nature, often being their fundamental step. For these reasons, research directed toward understanding the chiral anion recognition phenomenon may lead to the identification of structural patterns that enable increasingly efficient receptor design. In this review, we present the recent progress made in the area of synthetic receptors for biologically relevant chiral carboxylates.
format article
author Patryk Niedbała
Kajetan Dąbrowa
Sylwia Wasiłek
Janusz Jurczak
author_facet Patryk Niedbała
Kajetan Dąbrowa
Sylwia Wasiłek
Janusz Jurczak
author_sort Patryk Niedbała
title Recognition of Chiral Carboxylates by Synthetic Receptors
title_short Recognition of Chiral Carboxylates by Synthetic Receptors
title_full Recognition of Chiral Carboxylates by Synthetic Receptors
title_fullStr Recognition of Chiral Carboxylates by Synthetic Receptors
title_full_unstemmed Recognition of Chiral Carboxylates by Synthetic Receptors
title_sort recognition of chiral carboxylates by synthetic receptors
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/bb900298cbb04588b1bf48fee3dbd28e
work_keys_str_mv AT patrykniedbała recognitionofchiralcarboxylatesbysyntheticreceptors
AT kajetandabrowa recognitionofchiralcarboxylatesbysyntheticreceptors
AT sylwiawasiłek recognitionofchiralcarboxylatesbysyntheticreceptors
AT januszjurczak recognitionofchiralcarboxylatesbysyntheticreceptors
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