Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma

Abstract Development of anti-drug antibodies (ADAs) can interfere with therapeutic monoclonal antibodies and may lead to drug neutralisation and clinical disease progression. Measurement of circulating drug levels and development of ADAs in the setting of anti-programmed cell death-1 agent pembroliz...

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Main Authors: S. C. Sasson, L. E. Wilkins, R. A. Watson, C. Jolly, O. Brain, P. Klenerman, A. Olsson-Brown, B. P. Fairfax
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/bb9be8f3099e4082999b755983e9f62a
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