Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma
Abstract Development of anti-drug antibodies (ADAs) can interfere with therapeutic monoclonal antibodies and may lead to drug neutralisation and clinical disease progression. Measurement of circulating drug levels and development of ADAs in the setting of anti-programmed cell death-1 agent pembroliz...
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Auteurs principaux: | S. C. Sasson, L. E. Wilkins, R. A. Watson, C. Jolly, O. Brain, P. Klenerman, A. Olsson-Brown, B. P. Fairfax |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/bb9be8f3099e4082999b755983e9f62a |
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