Underlying mechanism of hemodynamics and intracranial aneurysm

Abstract In modern society, subarachnoid hemorrhage, mostly caused by intracranial aneurysm rupture, is accompanied by high disability and mortality rate, which has become a major threat to human health. Till now, the etiology of intracranial aneurysm has not been entirely clarified. In recent years...

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Autores principales:	Haishuang Tang, Qingsong Wang, Fengfeng Xu, Xiaoxi Zhang, Zhangwei Zeng, Yazhou Yan, Zhiwen Lu, Gaici Xue, Qiao Zuo, Yin Luo, Jianmin Liu, Qinghai Huang
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Hemodynamics Inflammation Atherosclerosis Intracranial aneurysm Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/bb9cf6281a8e4185897b5d6d77517c8d
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spelling	oai:doaj.org-article:bb9cf6281a8e4185897b5d6d77517c8d2021-12-05T12:16:49ZUnderlying mechanism of hemodynamics and intracranial aneurysm10.1186/s41016-021-00260-22057-4967https://doaj.org/article/bb9cf6281a8e4185897b5d6d77517c8d2021-12-01T00:00:00Zhttps://doi.org/10.1186/s41016-021-00260-2https://doaj.org/toc/2057-4967Abstract In modern society, subarachnoid hemorrhage, mostly caused by intracranial aneurysm rupture, is accompanied by high disability and mortality rate, which has become a major threat to human health. Till now, the etiology of intracranial aneurysm has not been entirely clarified. In recent years, more and more studies focus on the relationship between hemodynamics and intracranial aneurysm. Under the physiological condition, the mechanical force produced by the stable blood flow in the blood vessels keeps balance with the structure of the blood vessels. When the blood vessels are stimulated by the continuous abnormal blood flow, the functional structure of the blood vessels changes, which becomes the pathophysiological basis of the inflammation and atherosclerosis of the blood vessels and further promotes the occurrence and development of the intracranial aneurysm. This review will focus on the relationship between hemodynamics and intracranial aneurysms, will discuss the mechanism of occurrence and development of intracranial aneurysms, and will provide a new perspective for the research and treatment of intracranial aneurysms.Haishuang TangQingsong WangFengfeng XuXiaoxi ZhangZhangwei ZengYazhou YanZhiwen LuGaici XueQiao ZuoYin LuoJianmin LiuQinghai HuangBMCarticleHemodynamicsInflammationAtherosclerosisIntracranial aneurysmSurgeryRD1-811Neurology. Diseases of the nervous systemRC346-429ENChinese Neurosurgical Journal, Vol 7, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hemodynamics Inflammation Atherosclerosis Intracranial aneurysm Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Hemodynamics Inflammation Atherosclerosis Intracranial aneurysm Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429 Haishuang Tang Qingsong Wang Fengfeng Xu Xiaoxi Zhang Zhangwei Zeng Yazhou Yan Zhiwen Lu Gaici Xue Qiao Zuo Yin Luo Jianmin Liu Qinghai Huang Underlying mechanism of hemodynamics and intracranial aneurysm
description	Abstract In modern society, subarachnoid hemorrhage, mostly caused by intracranial aneurysm rupture, is accompanied by high disability and mortality rate, which has become a major threat to human health. Till now, the etiology of intracranial aneurysm has not been entirely clarified. In recent years, more and more studies focus on the relationship between hemodynamics and intracranial aneurysm. Under the physiological condition, the mechanical force produced by the stable blood flow in the blood vessels keeps balance with the structure of the blood vessels. When the blood vessels are stimulated by the continuous abnormal blood flow, the functional structure of the blood vessels changes, which becomes the pathophysiological basis of the inflammation and atherosclerosis of the blood vessels and further promotes the occurrence and development of the intracranial aneurysm. This review will focus on the relationship between hemodynamics and intracranial aneurysms, will discuss the mechanism of occurrence and development of intracranial aneurysms, and will provide a new perspective for the research and treatment of intracranial aneurysms.
format	article
author	Haishuang Tang Qingsong Wang Fengfeng Xu Xiaoxi Zhang Zhangwei Zeng Yazhou Yan Zhiwen Lu Gaici Xue Qiao Zuo Yin Luo Jianmin Liu Qinghai Huang
author_facet	Haishuang Tang Qingsong Wang Fengfeng Xu Xiaoxi Zhang Zhangwei Zeng Yazhou Yan Zhiwen Lu Gaici Xue Qiao Zuo Yin Luo Jianmin Liu Qinghai Huang
author_sort	Haishuang Tang
title	Underlying mechanism of hemodynamics and intracranial aneurysm
title_short	Underlying mechanism of hemodynamics and intracranial aneurysm
title_full	Underlying mechanism of hemodynamics and intracranial aneurysm
title_fullStr	Underlying mechanism of hemodynamics and intracranial aneurysm
title_full_unstemmed	Underlying mechanism of hemodynamics and intracranial aneurysm
title_sort	underlying mechanism of hemodynamics and intracranial aneurysm
publisher	BMC
publishDate	2021
url	https://doaj.org/article/bb9cf6281a8e4185897b5d6d77517c8d
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_version_	1718372099137994752

Underlying mechanism of hemodynamics and intracranial aneurysm

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