The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells

Transcription factor (TF) networks are essential for the molecular identity of each cell type. Here, the authors show that TF Nanog utilises multiple molecular strategies to enhance embryonic stem cell self-renewal, which include regulation of chromatin accessibility in the presence of LIF or mainte...

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Autores principales: Victor Heurtier, Nick Owens, Inma Gonzalez, Florian Mueller, Caroline Proux, Damien Mornico, Philippe Clerc, Agnes Dubois, Pablo Navarro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/bba6964391024d328a208f5b723bf1fc
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