Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays
Abstract Spreading depolarization (SD) is a slow propagating wave of strong depolarization of neural cells, implicated in several neuropathological conditions. The breakdown of brain homeostasis promotes significant hemodynamic and metabolic alterations, which impacts on neuronal function. In this w...
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Autores principales: | Cátia F. Lourenço, Ana Ledo, Greg A. Gerhardt, João Laranjinha, Rui M. Barbosa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/bba8403e168b4ea4bb2a7b8d57b7fc63 |
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