Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays

Abstract Spreading depolarization (SD) is a slow propagating wave of strong depolarization of neural cells, implicated in several neuropathological conditions. The breakdown of brain homeostasis promotes significant hemodynamic and metabolic alterations, which impacts on neuronal function. In this w...

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Bibliographic Details
Main Authors: Cátia F. Lourenço, Ana Ledo, Greg A. Gerhardt, João Laranjinha, Rui M. Barbosa
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/bba8403e168b4ea4bb2a7b8d57b7fc63
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