Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach

The treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully ide...

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Autores principales:	Xingxiang Pu, Sa Yang, Yan Xu, Bolin Chen, Qianzhi Wang, Qian Gong, Lin Wu
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	cancer of unknown primary gene expression profiling tissue of origin real-time PCR immunohistochemistry Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/bbb176fdc8934c0b8bd62aef73a0a013
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spelling	oai:doaj.org-article:bbb176fdc8934c0b8bd62aef73a0a0132021-11-11T08:11:10ZCase Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach2234-943X10.3389/fonc.2021.702887https://doaj.org/article/bbb176fdc8934c0b8bd62aef73a0a0132021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.702887/fullhttps://doaj.org/toc/2234-943XThe treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully identified with the corresponding primary tumor sites through gene expression profiling analysis. Then all patients received accurate treatment, providing reference to guide therapeutic decisions to treat CUP tumors in the future.Xingxiang PuSa YangYan XuBolin ChenQianzhi WangQian GongLin WuFrontiers Media S.A.articlecancer of unknown primarygene expression profilingtissue of originreal-time PCRimmunohistochemistryNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cancer of unknown primary gene expression profiling tissue of origin real-time PCR immunohistochemistry Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	cancer of unknown primary gene expression profiling tissue of origin real-time PCR immunohistochemistry Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Xingxiang Pu Sa Yang Yan Xu Bolin Chen Qianzhi Wang Qian Gong Lin Wu Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
description	The treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully identified with the corresponding primary tumor sites through gene expression profiling analysis. Then all patients received accurate treatment, providing reference to guide therapeutic decisions to treat CUP tumors in the future.
format	article
author	Xingxiang Pu Sa Yang Yan Xu Bolin Chen Qianzhi Wang Qian Gong Lin Wu
author_facet	Xingxiang Pu Sa Yang Yan Xu Bolin Chen Qianzhi Wang Qian Gong Lin Wu
author_sort	Xingxiang Pu
title	Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_short	Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_full	Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_fullStr	Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_full_unstemmed	Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_sort	case report: tissue origin identification for cancer of unknown primary: gene expression profiling approach
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/bbb176fdc8934c0b8bd62aef73a0a013
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Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach

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