Organotypic spinal cord cultures: An <em>in vitro</em> 3D model to preliminary screen treatments for spinal muscular atrophy
Spinal muscular atrophy (SMA) is a severe neuromuscular disease affecting children, due to mutation/deletion of survival motor neuron 1 (SMN1) gene. The lack of functional protein SMN determines motor neuron (MN) degeneration and skeletal muscle atrophy, leading to premature death due to respirator...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
PAGEPress Publications
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/bbba8f6e51404cb6b0df6e4954d4f06e |
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