Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparti...
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Nature Portfolio
2021
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oai:doaj.org-article:bbbb6cca9f2f42dcb9eebca5da1a48a82021-12-02T17:17:42ZCell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles10.1038/s41467-021-26052-x2041-1723https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a82021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26052-xhttps://doaj.org/toc/2041-1723Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparticles.Lizhi LiuXuan BaiMaria-Viola MartikainenAnna KårlundMarjut RoponenWujun XuGuoqing HuEnnio TasciottiVesa-Pekka LehtoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Lizhi Liu Xuan Bai Maria-Viola Martikainen Anna Kårlund Marjut Roponen Wujun Xu Guoqing Hu Ennio Tasciotti Vesa-Pekka Lehto Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
description |
Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparticles. |
format |
article |
author |
Lizhi Liu Xuan Bai Maria-Viola Martikainen Anna Kårlund Marjut Roponen Wujun Xu Guoqing Hu Ennio Tasciotti Vesa-Pekka Lehto |
author_facet |
Lizhi Liu Xuan Bai Maria-Viola Martikainen Anna Kårlund Marjut Roponen Wujun Xu Guoqing Hu Ennio Tasciotti Vesa-Pekka Lehto |
author_sort |
Lizhi Liu |
title |
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
title_short |
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
title_full |
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
title_fullStr |
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
title_full_unstemmed |
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
title_sort |
cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a8 |
work_keys_str_mv |
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_version_ |
1718381166136918016 |