Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparti...

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Main Authors: Lizhi Liu, Xuan Bai, Maria-Viola Martikainen, Anna Kårlund, Marjut Roponen, Wujun Xu, Guoqing Hu, Ennio Tasciotti, Vesa-Pekka Lehto
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a8
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spelling oai:doaj.org-article:bbbb6cca9f2f42dcb9eebca5da1a48a82021-12-02T17:17:42ZCell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles10.1038/s41467-021-26052-x2041-1723https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a82021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26052-xhttps://doaj.org/toc/2041-1723Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparticles.Lizhi LiuXuan BaiMaria-Viola MartikainenAnna KårlundMarjut RoponenWujun XuGuoqing HuEnnio TasciottiVesa-Pekka LehtoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lizhi Liu
Xuan Bai
Maria-Viola Martikainen
Anna Kårlund
Marjut Roponen
Wujun Xu
Guoqing Hu
Ennio Tasciotti
Vesa-Pekka Lehto
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
description Cell membrane coating of nanomaterials has become an attractive method of improving targeting, residence and biocompatibility. Here, the authors demonstrated that most nanoparticles are only partially coated by standard methods, and show the coating degree can impact the biological fate of nanoparticles.
format article
author Lizhi Liu
Xuan Bai
Maria-Viola Martikainen
Anna Kårlund
Marjut Roponen
Wujun Xu
Guoqing Hu
Ennio Tasciotti
Vesa-Pekka Lehto
author_facet Lizhi Liu
Xuan Bai
Maria-Viola Martikainen
Anna Kårlund
Marjut Roponen
Wujun Xu
Guoqing Hu
Ennio Tasciotti
Vesa-Pekka Lehto
author_sort Lizhi Liu
title Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
title_short Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
title_full Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
title_fullStr Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
title_full_unstemmed Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
title_sort cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bbbb6cca9f2f42dcb9eebca5da1a48a8
work_keys_str_mv AT lizhiliu cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT xuanbai cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT mariaviolamartikainen cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT annakarlund cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT marjutroponen cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT wujunxu cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT guoqinghu cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT enniotasciotti cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
AT vesapekkalehto cellmembranecoatingintegrityaffectstheinternalizationmechanismofbiomimeticnanoparticles
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