Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4<sup>+</sup> T Cell Activation and <italic toggle="yes">Mycobacterium tuberculosis</italic> Control

Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4<sup>+</sup> T Cell Activation and <italic toggle="yes">Mycobacterium tuberculosis</italic> Control

ABSTRACT Tuberculosis (TB) is one of the leading causes of death due to a single infectious agent. The development of a TB vaccine that induces durable and effective immunity to Mycobacterium tuberculosis (Mtb) infection is urgently needed. Early and superior Mtb control can be induced in M. bovis B...

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Auteurs principaux: Shibali Das, Nancy D. Marin, Ekaterina Esaulova, Mushtaq Ahmed, Amanda Swain, Bruce A. Rosa, Makedonka Mitreva, Javier Rangel-Moreno, Mihai G. Netea, Luis B. Barreiro, Maziar Divangahi, Maxim N. Artyomov, Deepak Kaushal, Shabaana A. Khader
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
Sujets:
tuberculosis
vaccine-induced response
clonality
parenchyma
epithelial cells
cytokines
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/bbbfc7050d474212917d0f59585b639e
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https://doaj.org/article/bbbfc7050d474212917d0f59585b639e

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