Grating-coupled interferometry reveals binding kinetics and affinities of Ni ions to genetically engineered protein layers

Abstract Reliable measurement of the binding kinetics of low molecular weight analytes to their targets is still a challenging task. Often, the introduction of labels is simply impossible in such measurements, and the application of label-free methods is the only reliable choice. By measuring the bi...

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Autores principales: Hajnalka Jankovics, Boglarka Kovacs, Andras Saftics, Tamas Gerecsei, Éva Tóth, Inna Szekacs, Ferenc Vonderviszt, Robert Horvath
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bbc0e199f2464a76b41617e43716222b
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