Co-translational assembly of mammalian nuclear multisubunit complexes

Genes encoding protein complex subunits are often dispersed in the genome of eukaryotes, raising the question how these protein complexes assemble. Here, the authors provide evidence that mammalian nuclear transcription complexes are formed co-translationally to ensure specific and functional intera...

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Autores principales:	Ivanka Kamenova, Pooja Mukherjee, Sascha Conic, Florian Mueller, Farrah El-Saafin, Paul Bardot, Jean-Marie Garnier, Doulaye Dembele, Simona Capponi, H. T. Marc Timmers, Stéphane D. Vincent, László Tora
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bbc82790458b46f6b41118387d376ef9
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spelling	oai:doaj.org-article:bbc82790458b46f6b41118387d376ef92021-12-02T14:38:37ZCo-translational assembly of mammalian nuclear multisubunit complexes10.1038/s41467-019-09749-y2041-1723https://doaj.org/article/bbc82790458b46f6b41118387d376ef92019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09749-yhttps://doaj.org/toc/2041-1723Genes encoding protein complex subunits are often dispersed in the genome of eukaryotes, raising the question how these protein complexes assemble. Here, the authors provide evidence that mammalian nuclear transcription complexes are formed co-translationally to ensure specific and functional interactions.Ivanka KamenovaPooja MukherjeeSascha ConicFlorian MuellerFarrah El-SaafinPaul BardotJean-Marie GarnierDoulaye DembeleSimona CapponiH. T. Marc TimmersStéphane D. VincentLászló ToraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ivanka Kamenova Pooja Mukherjee Sascha Conic Florian Mueller Farrah El-Saafin Paul Bardot Jean-Marie Garnier Doulaye Dembele Simona Capponi H. T. Marc Timmers Stéphane D. Vincent László Tora Co-translational assembly of mammalian nuclear multisubunit complexes
description	Genes encoding protein complex subunits are often dispersed in the genome of eukaryotes, raising the question how these protein complexes assemble. Here, the authors provide evidence that mammalian nuclear transcription complexes are formed co-translationally to ensure specific and functional interactions.
format	article
author	Ivanka Kamenova Pooja Mukherjee Sascha Conic Florian Mueller Farrah El-Saafin Paul Bardot Jean-Marie Garnier Doulaye Dembele Simona Capponi H. T. Marc Timmers Stéphane D. Vincent László Tora
author_facet	Ivanka Kamenova Pooja Mukherjee Sascha Conic Florian Mueller Farrah El-Saafin Paul Bardot Jean-Marie Garnier Doulaye Dembele Simona Capponi H. T. Marc Timmers Stéphane D. Vincent László Tora
author_sort	Ivanka Kamenova
title	Co-translational assembly of mammalian nuclear multisubunit complexes
title_short	Co-translational assembly of mammalian nuclear multisubunit complexes
title_full	Co-translational assembly of mammalian nuclear multisubunit complexes
title_fullStr	Co-translational assembly of mammalian nuclear multisubunit complexes
title_full_unstemmed	Co-translational assembly of mammalian nuclear multisubunit complexes
title_sort	co-translational assembly of mammalian nuclear multisubunit complexes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bbc82790458b46f6b41118387d376ef9
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Co-translational assembly of mammalian nuclear multisubunit complexes

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