Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

Elucidating how synaptic molecules such as AMPA receptors mediate neuronal communication and tracking their dynamic expression during behavior is crucial to understand cognition and disease, but current technological barriers preclude large-scale exploration of molecular dynamics in vivo. We have de...

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Bibliographic Details
Main Authors: Austin R Graves, Richard H Roth, Han L Tan, Qianwen Zhu, Alexei M Bygrave, Elena Lopez-Ortega, Ingie Hong, Alina C Spiegel, Richard C Johnson, Joshua T Vogelstein, Daniel J Tward, Michael I Miller, Richard L Huganir
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
synapse
plasticity
in vivo imaging
AMPA receptor
behavior
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/bbc936d28bba4fee99a9525f2f0b9c39
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