Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source

Abstract We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high...

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Autores principales:	Regine Gradl, Martin Dierolf, Lorenz Hehn, Benedikt Günther, Ali Önder Yildirim, Bernhard Gleich, Klaus Achterhold, Franz Pfeiffer, Kaye Susannah Morgan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bbccd0fb0fe24b03b8b648d118791e7f
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spelling	oai:doaj.org-article:bbccd0fb0fe24b03b8b648d118791e7f2021-12-02T15:06:03ZPropagation-based Phase-Contrast X-ray Imaging at a Compact Light Source10.1038/s41598-017-04739-w2045-2322https://doaj.org/article/bbccd0fb0fe24b03b8b648d118791e7f2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04739-whttps://doaj.org/toc/2045-2322Abstract We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 1010 ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures.Regine GradlMartin DierolfLorenz HehnBenedikt GüntherAli Önder YildirimBernhard GleichKlaus AchterholdFranz PfeifferKaye Susannah MorganNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Regine Gradl Martin Dierolf Lorenz Hehn Benedikt Günther Ali Önder Yildirim Bernhard Gleich Klaus Achterhold Franz Pfeiffer Kaye Susannah Morgan Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
description	Abstract We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 1010 ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures.
format	article
author	Regine Gradl Martin Dierolf Lorenz Hehn Benedikt Günther Ali Önder Yildirim Bernhard Gleich Klaus Achterhold Franz Pfeiffer Kaye Susannah Morgan
author_facet	Regine Gradl Martin Dierolf Lorenz Hehn Benedikt Günther Ali Önder Yildirim Bernhard Gleich Klaus Achterhold Franz Pfeiffer Kaye Susannah Morgan
author_sort	Regine Gradl
title	Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_short	Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_full	Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_fullStr	Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_full_unstemmed	Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source
title_sort	propagation-based phase-contrast x-ray imaging at a compact light source
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bbccd0fb0fe24b03b8b648d118791e7f
work_keys_str_mv	AT reginegradl propagationbasedphasecontrastxrayimagingatacompactlightsource AT martindierolf propagationbasedphasecontrastxrayimagingatacompactlightsource AT lorenzhehn propagationbasedphasecontrastxrayimagingatacompactlightsource AT benediktgunther propagationbasedphasecontrastxrayimagingatacompactlightsource AT alionderyildirim propagationbasedphasecontrastxrayimagingatacompactlightsource AT bernhardgleich propagationbasedphasecontrastxrayimagingatacompactlightsource AT klausachterhold propagationbasedphasecontrastxrayimagingatacompactlightsource AT franzpfeiffer propagationbasedphasecontrastxrayimagingatacompactlightsource AT kayesusannahmorgan propagationbasedphasecontrastxrayimagingatacompactlightsource
_version_	1718388606853185536

Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source

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