The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study

Abstract Objectives It has been known that the use of moisturizers is useful in preventing the onset and maintaining remission of atopic dermatitis (AD). We recently focused on the moisturizing effect of natural mineral dissolved water and have conducted various studies. In this study, we investigat...

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Autores principales:	Akihiko Uchiyama, Chisako Fujiwara, Yuta Inoue, Kazushi Uchida, Miyabi Hiyama, Hideyuki Itabashi, Sei‐ichiro Motegi
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	atopic dermatitis barrier dysfunction bathing dry skin natural mineral water Dermatology RL1-803 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/bbcf6efb05244b22a58d27a96d14c54a
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spelling	oai:doaj.org-article:bbcf6efb05244b22a58d27a96d14c54a2021-12-02T09:08:29ZThe effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study2574-459310.1002/cia2.12195https://doaj.org/article/bbcf6efb05244b22a58d27a96d14c54a2021-12-01T00:00:00Zhttps://doi.org/10.1002/cia2.12195https://doaj.org/toc/2574-4593Abstract Objectives It has been known that the use of moisturizers is useful in preventing the onset and maintaining remission of atopic dermatitis (AD). We recently focused on the moisturizing effect of natural mineral dissolved water and have conducted various studies. In this study, we investigated whether the bath treatment using natural mineral dissolved water can improve dry skin in AD patient in prospective nonblind, nonrandomized controlled study. Methods Thirteen adults with almost clear to moderate AD took bath therapy using tap water for 13 days, followed by bath therapy using natural mineral dissolved water for 13 days. Changes in the severity scoring, patient‐oriented eczema measure, pruritus numerical rating scale, transepidermal water loss (TEWL) and hydration were evaluated at day1, 14 and 28. Results Tap water using bath treatment did not change the severity scoring and itch associated score, and it partially decrease TEWL when compared with baseline condition. Bath treatment using natural mineral dissolved water slightly decrease eczema area and severity index (EASI) score and significantly decrease TEWL with respect to baseline condition. Moreover, in relatively severe AD analysis, bath treatment with mineral dissolved water significantly decreased EASI and TEWL. Conclusions Based on these results, bathing with natural mineral dissolved water may be effective in improving the dry skin of atopic dermatitis. Further studies are needed to evaluate its effects more clearly.Akihiko UchiyamaChisako FujiwaraYuta InoueKazushi UchidaMiyabi HiyamaHideyuki ItabashiSei‐ichiro MotegiWileyarticleatopic dermatitisbarrier dysfunctionbathingdry skinnatural mineral waterDermatologyRL1-803Immunologic diseases. AllergyRC581-607ENJournal of Cutaneous Immunology and Allergy, Vol 4, Iss 6, Pp 159-165 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	atopic dermatitis barrier dysfunction bathing dry skin natural mineral water Dermatology RL1-803 Immunologic diseases. Allergy RC581-607
spellingShingle	atopic dermatitis barrier dysfunction bathing dry skin natural mineral water Dermatology RL1-803 Immunologic diseases. Allergy RC581-607 Akihiko Uchiyama Chisako Fujiwara Yuta Inoue Kazushi Uchida Miyabi Hiyama Hideyuki Itabashi Sei‐ichiro Motegi The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
description	Abstract Objectives It has been known that the use of moisturizers is useful in preventing the onset and maintaining remission of atopic dermatitis (AD). We recently focused on the moisturizing effect of natural mineral dissolved water and have conducted various studies. In this study, we investigated whether the bath treatment using natural mineral dissolved water can improve dry skin in AD patient in prospective nonblind, nonrandomized controlled study. Methods Thirteen adults with almost clear to moderate AD took bath therapy using tap water for 13 days, followed by bath therapy using natural mineral dissolved water for 13 days. Changes in the severity scoring, patient‐oriented eczema measure, pruritus numerical rating scale, transepidermal water loss (TEWL) and hydration were evaluated at day1, 14 and 28. Results Tap water using bath treatment did not change the severity scoring and itch associated score, and it partially decrease TEWL when compared with baseline condition. Bath treatment using natural mineral dissolved water slightly decrease eczema area and severity index (EASI) score and significantly decrease TEWL with respect to baseline condition. Moreover, in relatively severe AD analysis, bath treatment with mineral dissolved water significantly decreased EASI and TEWL. Conclusions Based on these results, bathing with natural mineral dissolved water may be effective in improving the dry skin of atopic dermatitis. Further studies are needed to evaluate its effects more clearly.
format	article
author	Akihiko Uchiyama Chisako Fujiwara Yuta Inoue Kazushi Uchida Miyabi Hiyama Hideyuki Itabashi Sei‐ichiro Motegi
author_facet	Akihiko Uchiyama Chisako Fujiwara Yuta Inoue Kazushi Uchida Miyabi Hiyama Hideyuki Itabashi Sei‐ichiro Motegi
author_sort	Akihiko Uchiyama
title	The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
title_short	The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
title_full	The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
title_fullStr	The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
title_full_unstemmed	The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study
title_sort	effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: a phase iia, nonrandomized, controlled study
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/bbcf6efb05244b22a58d27a96d14c54a
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The effect of balneotherapy with natural mineral dissolved water on dry skin in atopic dermatitis: A phase IIa, nonrandomized, controlled study

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