Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells
The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous...
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Nature Portfolio
2016
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oai:doaj.org-article:bbd6d036c48243b1b66504db2d372bae2021-12-02T14:39:32ZActive diffusion and microtubule-based transport oppose myosin forces to position organelles in cells10.1038/ncomms118142041-1723https://doaj.org/article/bbd6d036c48243b1b66504db2d372bae2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11814https://doaj.org/toc/2041-1723The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous fungi.Congping LinMartin SchusterSofia Cunha GuimaraesPeter AshwinMichael SchraderJeremy MetzChristian HackerSarah Jane GurrGero SteinbergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Congping Lin Martin Schuster Sofia Cunha Guimaraes Peter Ashwin Michael Schrader Jeremy Metz Christian Hacker Sarah Jane Gurr Gero Steinberg Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
description |
The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous fungi. |
format |
article |
author |
Congping Lin Martin Schuster Sofia Cunha Guimaraes Peter Ashwin Michael Schrader Jeremy Metz Christian Hacker Sarah Jane Gurr Gero Steinberg |
author_facet |
Congping Lin Martin Schuster Sofia Cunha Guimaraes Peter Ashwin Michael Schrader Jeremy Metz Christian Hacker Sarah Jane Gurr Gero Steinberg |
author_sort |
Congping Lin |
title |
Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
title_short |
Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
title_full |
Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
title_fullStr |
Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
title_full_unstemmed |
Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
title_sort |
active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/bbd6d036c48243b1b66504db2d372bae |
work_keys_str_mv |
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1718390614035267584 |