Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

Classical Hodgkin lymphoma is a cancer that originates in lymph nodes. Little is known about its genetic susceptibility. Here, the authors combined existing and new genome-wide association studies to identify risk loci for classical Hodgkin lymphoma at 6q22.33, and nodular sclerosis Hodgkin lymphoma...

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Autores principales:	Amit Sud, Hauke Thomsen, Philip J. Law, Asta Försti, Miguel Inacio da Silva Filho, Amy Holroyd, Peter Broderick, Giulia Orlando, Oleg Lenive, Lauren Wright, Rosie Cooke, Douglas Easton, Paul Pharoah, Alison Dunning, Julian Peto, Federico Canzian, Rosalind Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, The PRACTICAL consortium, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Elke Pogge von Strandmann, Tracy Lightfoot, Eleanor Kane, Eve Roman, Annette Lake, Dorothy Montgomery, Ruth F. Jarrett, Anthony J. Swerdlow, Andreas Engert, Nick Orr, Kari Hemminki, Richard S. Houlston
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bbd8c74bc7f7447a851d248b1b176093
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spelling	oai:doaj.org-article:bbd8c74bc7f7447a851d248b1b1760932021-12-02T15:39:06ZGenome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility10.1038/s41467-017-00320-12041-1723https://doaj.org/article/bbd8c74bc7f7447a851d248b1b1760932017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00320-1https://doaj.org/toc/2041-1723Classical Hodgkin lymphoma is a cancer that originates in lymph nodes. Little is known about its genetic susceptibility. Here, the authors combined existing and new genome-wide association studies to identify risk loci for classical Hodgkin lymphoma at 6q22.33, and nodular sclerosis Hodgkin lymphoma at 3q28, 6q23.3, 10p14, 13q34, 16p13.13.Amit SudHauke ThomsenPhilip J. LawAsta FörstiMiguel Inacio da Silva FilhoAmy HolroydPeter BroderickGiulia OrlandoOleg LeniveLauren WrightRosie CookeDouglas EastonPaul PharoahAlison DunningJulian PetoFederico CanzianRosalind EelesZSofia Kote-JaraiKenneth MuirNora PashayanThe PRACTICAL consortiumPer HoffmannMarkus M. NöthenKarl-Heinz JöckelElke Pogge von StrandmannTracy LightfootEleanor KaneEve RomanAnnette LakeDorothy MontgomeryRuth F. JarrettAnthony J. SwerdlowAndreas EngertNick OrrKari HemminkiRichard S. HoulstonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amit Sud Hauke Thomsen Philip J. Law Asta Försti Miguel Inacio da Silva Filho Amy Holroyd Peter Broderick Giulia Orlando Oleg Lenive Lauren Wright Rosie Cooke Douglas Easton Paul Pharoah Alison Dunning Julian Peto Federico Canzian Rosalind Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL consortium Per Hoffmann Markus M. Nöthen Karl-Heinz Jöckel Elke Pogge von Strandmann Tracy Lightfoot Eleanor Kane Eve Roman Annette Lake Dorothy Montgomery Ruth F. Jarrett Anthony J. Swerdlow Andreas Engert Nick Orr Kari Hemminki Richard S. Houlston Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
description	Classical Hodgkin lymphoma is a cancer that originates in lymph nodes. Little is known about its genetic susceptibility. Here, the authors combined existing and new genome-wide association studies to identify risk loci for classical Hodgkin lymphoma at 6q22.33, and nodular sclerosis Hodgkin lymphoma at 3q28, 6q23.3, 10p14, 13q34, 16p13.13.
format	article
author	Amit Sud Hauke Thomsen Philip J. Law Asta Försti Miguel Inacio da Silva Filho Amy Holroyd Peter Broderick Giulia Orlando Oleg Lenive Lauren Wright Rosie Cooke Douglas Easton Paul Pharoah Alison Dunning Julian Peto Federico Canzian Rosalind Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL consortium Per Hoffmann Markus M. Nöthen Karl-Heinz Jöckel Elke Pogge von Strandmann Tracy Lightfoot Eleanor Kane Eve Roman Annette Lake Dorothy Montgomery Ruth F. Jarrett Anthony J. Swerdlow Andreas Engert Nick Orr Kari Hemminki Richard S. Houlston
author_facet	Amit Sud Hauke Thomsen Philip J. Law Asta Försti Miguel Inacio da Silva Filho Amy Holroyd Peter Broderick Giulia Orlando Oleg Lenive Lauren Wright Rosie Cooke Douglas Easton Paul Pharoah Alison Dunning Julian Peto Federico Canzian Rosalind Eeles ZSofia Kote-Jarai Kenneth Muir Nora Pashayan The PRACTICAL consortium Per Hoffmann Markus M. Nöthen Karl-Heinz Jöckel Elke Pogge von Strandmann Tracy Lightfoot Eleanor Kane Eve Roman Annette Lake Dorothy Montgomery Ruth F. Jarrett Anthony J. Swerdlow Andreas Engert Nick Orr Kari Hemminki Richard S. Houlston
author_sort	Amit Sud
title	Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
title_short	Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
title_full	Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
title_fullStr	Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
title_full_unstemmed	Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
title_sort	genome-wide association study of classical hodgkin lymphoma identifies key regulators of disease susceptibility
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bbd8c74bc7f7447a851d248b1b176093
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Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

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