EEG-based visual deviance detection in freely behaving mice

The mouse is widely used as an experimental model to study visual processing. To probe how the visual system detects changes in the environment, functional paradigms in freely behaving mice are strongly needed. We developed and validated the first EEG-based method to investigate visual deviance dete...

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Autores principales:	Renate Kat, Berry van den Berg, Matthijs JL Perenboom, Maarten Schenke, Arn MJM van den Maagdenberg, Hilgo Bruining, Else A Tolner, Martien JH Kas
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Visual processing Mismatch negativity Sensory processing deficits Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/bbdcc659720a48fa8d88b9360c496b50
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id	oai:doaj.org-article:bbdcc659720a48fa8d88b9360c496b50
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spelling	oai:doaj.org-article:bbdcc659720a48fa8d88b9360c496b502021-11-28T04:29:14ZEEG-based visual deviance detection in freely behaving mice1095-957210.1016/j.neuroimage.2021.118757https://doaj.org/article/bbdcc659720a48fa8d88b9360c496b502021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1053811921010296https://doaj.org/toc/1095-9572The mouse is widely used as an experimental model to study visual processing. To probe how the visual system detects changes in the environment, functional paradigms in freely behaving mice are strongly needed. We developed and validated the first EEG-based method to investigate visual deviance detection in freely behaving mice. Mice with EEG implants were exposed to a visual deviant detection paradigm that involved changes in light intensity as standard and deviant stimuli. By subtracting the standard from the deviant evoked waveform, deviant detection was evident as bi-phasic negativity (starting around 70 ms) in the difference waveform. Additionally, deviance-associated evoked (beta/gamma) and induced (gamma) oscillatory responses were found. We showed that the results were stimulus-independent by applying a “flip-flop” design and the results showed good repeatability in an independent measurement. Together, we put forward a validated, easy-to-use paradigm to measure visual deviance processing in freely behaving mice.Renate KatBerry van den BergMatthijs JL PerenboomMaarten SchenkeArn MJM van den MaagdenbergHilgo BruiningElse A TolnerMartien JH KasElsevierarticleVisual processingMismatch negativitySensory processing deficitsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENNeuroImage, Vol 245, Iss , Pp 118757- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Visual processing Mismatch negativity Sensory processing deficits Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	Visual processing Mismatch negativity Sensory processing deficits Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Renate Kat Berry van den Berg Matthijs JL Perenboom Maarten Schenke Arn MJM van den Maagdenberg Hilgo Bruining Else A Tolner Martien JH Kas EEG-based visual deviance detection in freely behaving mice
description	The mouse is widely used as an experimental model to study visual processing. To probe how the visual system detects changes in the environment, functional paradigms in freely behaving mice are strongly needed. We developed and validated the first EEG-based method to investigate visual deviance detection in freely behaving mice. Mice with EEG implants were exposed to a visual deviant detection paradigm that involved changes in light intensity as standard and deviant stimuli. By subtracting the standard from the deviant evoked waveform, deviant detection was evident as bi-phasic negativity (starting around 70 ms) in the difference waveform. Additionally, deviance-associated evoked (beta/gamma) and induced (gamma) oscillatory responses were found. We showed that the results were stimulus-independent by applying a “flip-flop” design and the results showed good repeatability in an independent measurement. Together, we put forward a validated, easy-to-use paradigm to measure visual deviance processing in freely behaving mice.
format	article
author	Renate Kat Berry van den Berg Matthijs JL Perenboom Maarten Schenke Arn MJM van den Maagdenberg Hilgo Bruining Else A Tolner Martien JH Kas
author_facet	Renate Kat Berry van den Berg Matthijs JL Perenboom Maarten Schenke Arn MJM van den Maagdenberg Hilgo Bruining Else A Tolner Martien JH Kas
author_sort	Renate Kat
title	EEG-based visual deviance detection in freely behaving mice
title_short	EEG-based visual deviance detection in freely behaving mice
title_full	EEG-based visual deviance detection in freely behaving mice
title_fullStr	EEG-based visual deviance detection in freely behaving mice
title_full_unstemmed	EEG-based visual deviance detection in freely behaving mice
title_sort	eeg-based visual deviance detection in freely behaving mice
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/bbdcc659720a48fa8d88b9360c496b50
work_keys_str_mv	AT renatekat eegbasedvisualdeviancedetectioninfreelybehavingmice AT berryvandenberg eegbasedvisualdeviancedetectioninfreelybehavingmice AT matthijsjlperenboom eegbasedvisualdeviancedetectioninfreelybehavingmice AT maartenschenke eegbasedvisualdeviancedetectioninfreelybehavingmice AT arnmjmvandenmaagdenberg eegbasedvisualdeviancedetectioninfreelybehavingmice AT hilgobruining eegbasedvisualdeviancedetectioninfreelybehavingmice AT elseatolner eegbasedvisualdeviancedetectioninfreelybehavingmice AT martienjhkas eegbasedvisualdeviancedetectioninfreelybehavingmice
_version_	1718408404532199424

EEG-based visual deviance detection in freely behaving mice

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